Pil’o, S. G.; Brovarets, V. S.; Romanenko, E. A.; Drach, B. S. published the artcile< Reaction of 3,3-dichloro-2-[(dichloroacetyl)amino]acrylonitrile with amines>, Electric Literature of 10574-69-3, the main research area is oxazolecarbonitrile derivative preparation hydrolysis condensation reaction; polychlorinated enamidonitrile heterocyclization amine.
Polychlorinated enamidonitrile Cl2C:C(CN)NHCOCHCl2 readily reacts with primary aromatic amines, dialkylamines, piperidine, and morpholine. The reaction is accompanied by complete elimination of chlorine atoms as chloride ions with formation of 4-cyanooxazoles having the corresponding amine residue in position 5 of the ring and a CH:N or diaminomethyl moiety in position 2. The structure of 5-arylamino(dialkylamino)-4-cyano-2-formyloxazoles was confirmed by their acid hydrolysis, as well as by condensation with phenylhydrazine, N-alkylrhodanines, and Et acetoacetate in the presence of urea.
Russian Journal of General Chemistry (Translation of Zhurnal Obshchei Khimii) published new progress about Aromatic amines Role: RCT (Reactant), RACT (Reactant or Reagent). 10574-69-3 belongs to class thiazole, and the molecular formula is C10H9NOS2, Electric Literature of 10574-69-3.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica