Sarkar, Sudeep; Wojciechowska, Natalia; Rajkiewicz, Adam A.; Kalek, Marcin published the artcile< Synthesis of Aryl Sulfides by Metal-Free Arylation of Thiols with Diaryliodonium Salts under Basic Conditions>, Electric Literature of 96-53-7, the main research area is aryl sulfide preparation DFT; thiol diaryliodonium salt arylation.
Metal-free arylation of thiols RSH (R = n-Bu, Bn, 2,3-dihydro-1,3-benzothiazol-2-yl, etc.) with diaryliodonium salts (Ar)2I+TfO-(Ar = 2,4,6-trimethylphenyl, 2-fluorophenyl, 4-nitrophenyl, etc.) have been developed. The application of a strong organic base enables the C-S bond formation under mild and exptl. simple conditions. The method allows for the synthesis of aryl sulfides R1SAr containing a broad range of aryl groups from an array of thiols, including aryl, heteroaryl, and alkyl ones. The mechanism of the reaction was studied by DFT calculations, demonstrating that it proceeds via the inner sphere pathway involving formation of an Ar2I(SR) intermediate, followed by reductive elimination.
European Journal of Organic Chemistry published new progress about Arylation. 96-53-7 belongs to class thiazole, and the molecular formula is C3H5NS2, Electric Literature of 96-53-7.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica