3034-48-8, 2-Bromo-5-nitrothiazole is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
(1) 1-(5-Nitrothiazol-2-yl)piperazine To a solution of piperazine (18.2 g) and potassium carbonate (12.6 g) in acetonitrile (150 ml) was added 2-bromo-5-nitrothiazole (14.7 g) at 40¡ã C. and the mixture was stirred at 60¡ã C. for 40 min. The reaction mixture was poured into water and extracted with chloroform. The extract was washed with saturated brine and dried over anhydrous sodium sulfate. The solvent was evaporated to give a brown solid (11.2 g). The obtained brown solid was purified by silica gel column chromatography (developing solvent; chloroform_methanol=9:1) to give the title compound (4.8 g) as yellow crystals. 1H-NMR(DMSO-d6)(delta: 2.80(4H, t, J=5.3 Hz), 3.55(4H, t, J=5.3 Hz), 8.37(1H, s); MS(EI): 214(M+);
As the paragraph descriping shows that 3034-48-8 is playing an increasingly important role.
Reference£º
Patent; Mitsubishi Pharma Corporation; US6455528; (2002); B1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica