In 2006,Barrett, Olivia J.; Childs, Jessica L.; Disney, Matthew D. published 《Chemical microarrays to identify ligands that bind pathogenic cells》.ChemBioChem published the findings.SDS of cas: 3034-22-8 The information in the text is summarized as follows:
The use of microarrays to identify new ligands for cells by interrogating their binding to a library of organic ligands is described. The advantages of using microarrays include assay miniaturization and the manner in which ligands are displayed in a small area. This display mimics interactions that occur at cell-cell interfaces and amplifies binding affinities. In addition, a series of array surfaces was tested for resisting nonspecific binding, which includes amine-, BSA, and agarose- (aldehyde-) coated glass, plain glass, and glass coated with ethanolamine prepared in a two-step procedures from amine-coated slides using the pathogenic Pseudomonas aeruginosa, which forms sticky biofilms. The agarose slides offer an alternative as a more general arraying substrate to study the binding of microarray-immobilized ligands to cells. After reading the article, we found that the author used 5-Bromothiazol-2-amine(cas: 3034-22-8SDS of cas: 3034-22-8)
5-Bromothiazol-2-amine(cas: 3034-22-8) belongs to anime. Amines can be classified according to the nature and number of substituents on nitrogen. Aliphatic amines contain only H and alkyl substituents. Aromatic amines have the nitrogen atom connected to an aromatic ring.Important amines include amino acids, biogenic amines, trimethylamine, and aniline. Inorganic derivatives of ammonia are also called amines, such as monochloramine (NClH2).SDS of cas: 3034-22-8
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica