《Flow hydrodediazoniation of aromatic heterocycles》 was published in Molecules in 2019. These research results belong to Roeder, Liesa; Nicholls, Alexander J.; Baxendale, Ian R.. SDS of cas: 95-24-9 The article mentions the following:
Continuous flow processing was applied for the rapid replacement of an aromatic amino group with a hydride. The approach was applied to a range of aromatic heterocycles RNH2 (R = 1,3-benzoxazol-2-yl, 2-pyridyl, 4-cyano-1-phenyl-1H-1,2,3-triazol-5-yl, etc.) confirming the wide scope and substituent-tolerance of the processes. Flow equipment was utilized and the process optimized to overcome the problematically-unstable intermediates that have restricted yields in previous studies relying on batch procedures. Various common organic solvents were investigated as potential hydride sources. The approach has allowed key structures, such as amino-pyrazoles and aminopyridines to be deaminated in good yield using a purely organic-soluble system.6-Chlorobenzothiazol-2-ylamine(cas: 95-24-9SDS of cas: 95-24-9) was used in this study.
6-Chlorobenzothiazol-2-ylamine(cas: 95-24-9) belongs to thiazoles. Thiazoles are a class of five-membered rings containing nitrogen and sulfur with excellent antitumor, antiviral and antibiotic activities.SDS of cas: 95-24-9Thiazoles can also be used as protected formyl groups, which can be released in later stages of complex natural product synthesis.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica