On March 31, 2020, Borthakur, Susanta Kumar; Kalita, Pabitra Kumar; Borthakur, Sukanya published an article.Category: thiazole The title of the article was Synthesis and antifungal activities of 3,5-diphenyl-7-amino-[1,3]-thiazolo[3,2-a]pyrimidine-6-nitrile derivatives. And the article contained the following:
A series of novel 3,7-diphenyl-7-amino[1,3]thiazolo[3,2-a]pyrimidine-6-nitrile derivatives I [R = H, 4-Me, 4-OMe, etc.] was synthesized by refluxing 2-amino-4-phenyl-1,3-thiazole and arylidinemalononitriles in propanol using NaOH as catalyst. Antifungal activities of the synthesized compounds were done by testing against Rhizoctonia solani and Drechslera orazae, two fungal pathogens causing diseases on rice crops. Among the tested compounds, compounds I [R = 4-Cl, 4-NMe2, 4-OMe, 3-OMe-4-OH] showed good to moderate antifungal activity. The experimental process involved the reaction of 4-Phenylthiazol-2-amine(cas: 2010-06-2).Category: thiazole
The Article related to diphenyl amino thiazolopyrimidine nitrile preparation antifungal, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Category: thiazole
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica