On July 27, 2022, Wang, Xingyi; Zhu, Yue; Zhou, Tingting; Yang, Weiqing; Fu, Haiyan; Chen, Hua; Ma, Menglin published an article.Application of 31699-14-6 The title of the article was Bromine-Mediated C-S Bond Formation: Synthesis of Thiazoles from α-Methylene Ketones by Using Oxone Oxidative System. And the article contained the following:
A novel method for the synthesis of various 2,4,5-trisubstituted thiazoles from methylketones and thiourea/thioacetamide/amidinothiourea using NaBr/Oxone oxidative system was developed. The three intimately connected advantages of this method, which form a whole, are that the reaction underwent a one-pot α-bromination/cyclization process, the use of more common methylene ketones as the raw material rather than α-halomethylene ketones and a cheap and easily available catalytic amount sodium bromide as the bromine source instead of stoichiometric bromine or NBS. The experimental process involved the reaction of 2-Amino-4-(4-iodophenyl)thiazole(cas: 31699-14-6).Application of 31699-14-6
The Article related to ethanone methanethioamide sodium bromide catalyst one pot bromination heterocyclization, thiazole preparation, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Application of 31699-14-6
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica