On November 26, 2015, Lin, Songnian; Parmee, Emma R.; Xu, Jiayi published a patent.Application In Synthesis of Ethyl 2-((2-aminothiazol-5-yl)thio)acetate The title of the patent was Novel 2-pyridinecarboxamide derivatives, compositions containing such compounds, and methods of treatment. And the patent contained the following:
Novel pyridine-2-carboxamide derivatives of formula I and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are effective as glucokinase activating agents. Pharmaceutical compositions and methods of treatment are also included. The present invention relates to novel pyridine-2-carboxamide derivatives and salts thereof which are effective as glucokinase activating agents. Moreover, it relates to compositions containing such compounds, and methods of treatment. The experimental process involved the reaction of Ethyl 2-((2-aminothiazol-5-yl)thio)acetate(cas: 859522-19-3).Application In Synthesis of Ethyl 2-((2-aminothiazol-5-yl)thio)acetate
The Article related to pyridinecarboxamide preparation glucokinase activator antidiabetic antiobesity, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Application In Synthesis of Ethyl 2-((2-aminothiazol-5-yl)thio)acetate
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica