On November 24, 2017, Liu, Denggui; Yang, Kunyu; Zhou, Wei; Chen, Hao; Zeng, Qingdong published a patent.Quality Control of Ethyl 2-(4-methylpent-2-enoyl)thiazole-4-carboxylate The title of the patent was Preparation of 2-(4-methyl-1-oxo-2-penten-1-yl)-4-thiazolecarboxylic acid ethyl ester. And the patent contained the following:
The invention discloses a preparation method of anti-cancer medicament intermediate, using glyceraldehyde acetonide and L-cysteine hydrochloride as raw materials, through steps such as cyclization, oxidation, de-propylidene, reoxidizing, and halohydrin to obtain an intermediate compound, which was further reacted with isobutyric aldehyde through Wittig, and compound 2-(4-methyl-1-oxo-2-penten-1-yl)-4-thiazolecarboxylic acid Et ester is obtained. The experimental process involved the reaction of Ethyl 2-(4-methylpent-2-enoyl)thiazole-4-carboxylate(cas: 944559-46-0).Quality Control of Ethyl 2-(4-methylpent-2-enoyl)thiazole-4-carboxylate
The Article related to thiazolecarboxylic acid ethyl ester preparation, Amino Acids, Peptides, and Proteins: Amino Acids and other aspects.Quality Control of Ethyl 2-(4-methylpent-2-enoyl)thiazole-4-carboxylate
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica