On April 30, 2021, Cho, Su-Hyeon; Kim, Song Rae; Jeong, Myeong Seon; Choi, Miri; Park, SeonJu; Kim, Kil-Nam published an article.Reference of 2-Acetylthiazole The title of the article was Protective Effect of Brassica napus L. Hydrosols against Inflammation Response in RAW 264.7 Cells. And the article contained the following:
To demonstrate the anti-inflammatory activity of Brassica napus L. hydrosols (BNH) in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. Composition anal. of BNH was conducted via gas chromatog.-mass spectrometry after BNH were extracted The nitric oxide (NO) production was measured using the Griess assay. Prostaglandin E2 (PGE2) production was evaluated with ELISA. The effects of BNH on LPS-induced pro-inflammatory enzymes including inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) were evaluated using Western blot anal. Furthermore, phosphorylation of nuclear factor-kappa B (NF-κB) and nuclear translocation of NF-κB p65 were evaluated with Western blot anal. and immunofluorescence staining, resp. Compared with LPS-stimulated cells, BNH markedly decreased the generation of NO and PGE2 in LPS-stimulated RAW 264.7 cells (P<0.01 or P<0.05). Moreover, BNH inhibited protein levels of iNOS and COX-2 (P<0.01). Phosphorylation of NF-κB and nuclear translocation of NF-κB p65 was significantly inhibited by BNH (P<0.01 or P<0.05). The anti-inflammatory activities of BNH were mediated via blockage of the NF-κB signaling pathways in LPS-stimulated RAW 264.7 cells. The experimental process involved the reaction of 2-Acetylthiazole(cas: 24295-03-2).Reference of 2-Acetylthiazole
The Article related to brassica napus hydrosols inflammation lipopolysaccharide, brassica napus l., raw 264.7 cells, hydrosols, inflammation, lipopolysaccharide, Placeholder for records without volume info and other aspects.Reference of 2-Acetylthiazole
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica