On July 31, 2009, Kamber, Markus; Flueckiger-Isler, Sini; Engelhardt, Guenter; Jaeckh, Rudolf; Zeiger, Errol published an article.SDS of cas: 92-36-4 The title of the article was Comparison of the Ames II and traditional Ames test responses with respect to mutagenicity, strain specificities, need for metabolism and correlation with rodent carcinogenicity. And the article contained the following:
The Ames II Salmonella mutagenicity assay procedure was used to test 71 chems., and the results were compared with those from the traditional Ames Salmonella test using the NTP database as the reference All Ames II tests were performed using a fluctuation procedure in microplate format, using TAMix for the detection of base pair substitutions and TA98 to detect frameshift mutations. There was 84% agreement between the two procedures in identifying mutagens and nonmutagens, which is equivalent to the intra- and interlaboratory reproducibility of 87% for the traditional test. The two tests also performed similarly in their predictions of rodent carcinogenicity. The experimental process involved the reaction of 2-(4-Aminophenyl)-6-methylbenzothiazole(cas: 92-36-4).SDS of cas: 92-36-4
The Article related to salmonella strain ames ii mutagenicity metabolism, rodent carcinogenicity ames test predictivity mutagen, Toxicology: Methods (Including Analysis) and other aspects.SDS of cas: 92-36-4
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica