Li, Yongyi; Yao, Wanyou; Ou, Shuilian; Huang, Xuezhen published an article in 2019, the title of the article was Correlation analysis of APTT, PT and other coagulation related indicators with the occurrence of prethrombus in pregnant women.Electric Literature of 92-36-4 And the article contains the following content:
Objective To analyze the changes of activated partial thromboplastin time (APTT), prothrombin time (PT) and other coagulation related indexes in pregnant women with prethrombus state during pregnancy, and to explore the correlation between them. Methods 60 pregnant women with prethrombotic condition (diagnosed by ultrasound) and 100 normal pregnant women who underwent phys. examination in the Department of Obstetrics and Gynecol. of our hospital from Jan. 2017 to Oct. 2018 were enrolled as study subjects. They were divided into the prethrombotic condition group and the normal pregnancy group. The prethrombotic status indicators of pregnant women in the two groups were detected by ELISA: d-dimer (D-D). Immunoturbidimetry method was used to detect coagulant function indexes, such as prothrombin time (PT), activated partial clotting enzyme live time (APTT), thrombin time (TT), fibrinogen (FBG) and antithrombin III (AT-III) . These indexes of the two groups of pregnant women were compared and analyzed by correlation method, which provided the basis for expounding the correlation between the changes of coagulation function indexes and the occurrence of prethrombus state. Results There was no significant difference in TT, PT and FBG between prethrombus state group and normal pregnancy group (P>0.05). APTT and AT-III in the prethrombus state group was (22.4±3.3) s and (76.3±5.7) %, which was lower than those in the normal pregnancy group (26.4±2.1) s and (92.3±6.4) %, which was neg. correlated with the occurrence of prethrombus state, with statistically significant difference (P<0.05). The D-D level in the prethrombotic condition group was higher than that in the normal pregnancy group, which was pos. correlated with the occurrence of prethrombotic state, and the difference was statistically significant (P<0.05). Conclusion The anomaly of APTT, AT-III and D-D is an important index to suggest the occurrence of prethrombotic state, and thus checking for changes of their levels is of great significance for predicting early pregnancy thrombosis and making reasonable delivery plan. The experimental process involved the reaction of 2-(4-Aminophenyl)-6-methylbenzothiazole(cas: 92-36-4).Electric Literature of 92-36-4
2-(4-Aminophenyl)-6-methylbenzothiazole(cas:92-36-4) belongs to thiazole. Thiazole rings are planar and aromatic. Thiazoles are characterized by larger pi-electron delocalization than the corresponding oxazoles and have therefore greater aromaticity. Electric Literature of 92-36-4
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica