Wang, Xingyi published the artcileBromine-Mediated C-S Bond Formation: Synthesis of Thiazoles from α-Methylene Ketones by Using Oxone Oxidative System, SDS of cas: 90323-06-1, the main research area is ethanone methanethioamide sodium bromide catalyst one pot bromination heterocyclization; thiazole preparation.
A novel method for the synthesis of various 2,4,5-trisubstituted thiazoles from methylketones and thiourea/thioacetamide/amidinothiourea using NaBr/Oxone oxidative system was developed. The three intimately connected advantages of this method, which form a whole, are that the reaction underwent a one-pot α-bromination/cyclization process, the use of more common methylene ketones as the raw material rather than α-halomethylene ketones and a cheap and easily available catalytic amount sodium bromide as the bromine source instead of stoichiometric bromine or NBS.
ChemistrySelect published new progress about C-S bond formation. 90323-06-1 belongs to class thiazole, name is 4-(2-Nitrophenyl)thiazole-2-amine, and the molecular formula is C9H7N3O2S, SDS of cas: 90323-06-1.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica