Watson, Keith J.’s team published research in Macromolecules in 34 | CAS: 92-36-4

Macromolecules published new progress about 92-36-4. 92-36-4 belongs to thiazole, auxiliary class Organic Pigment, name is 2-(4-Aminophenyl)-6-methylbenzothiazole, and the molecular formula is C5H9IO2, Synthetic Route of 92-36-4.

Watson, Keith J. published the artcileToward Polymeric Anticancer Drug Cocktails from Ring-Opening Metathesis Polymerization, Synthetic Route of 92-36-4, the publication is Macromolecules (2001), 34(11), 3507-3509, database is CAplus.

Exo-5-norbornene-2-ol was used to modify 3 anticancer drugs (i.e., indomethacin, 2-(4-aminophenyl)-6-methylbenzothiazole, and chlorambucil) with respect to preparation of polymer-based drug delivery systems. The modified drugs were polymerized using a Ru carbene (Cl2(PCy3)2Ru=CHPh) as initiator in a living ring-opening metathesis polymerization The norbornene-derived drugs were amenable to the synthesis of either block copolymers in combination with each other or random copolymers in combination with a norbornenyl-modified triethylene glycol monomer.

Macromolecules published new progress about 92-36-4. 92-36-4 belongs to thiazole, auxiliary class Organic Pigment, name is 2-(4-Aminophenyl)-6-methylbenzothiazole, and the molecular formula is C5H9IO2, Synthetic Route of 92-36-4.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica