Smith, Adrian L. published the artcileDiscovery of 1H-Pyrazol-3(2H)-ones as Potent and Selective Inhibitors of Protein Kinase R-like Endoplasmic Reticulum Kinase (PERK), Quality Control of 791614-90-9, the publication is Journal of Medicinal Chemistry (2015), 58(3), 1426-1441, database is CAplus and MEDLINE.
The structure-based design and optimization of a novel series of selective PERK inhibitors are described resulting in the identification of I as a potent, highly selective, and orally active tool compound suitable for PERK pathway biol. exploration both in vitro and in vivo.
Journal of Medicinal Chemistry published new progress about 791614-90-9. 791614-90-9 belongs to thiazole, auxiliary class Boronate Esters,Boronic acid and ester,Boronic acid and ester, name is 2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole, and the molecular formula is C7H13NO2, Quality Control of 791614-90-9.
Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica