Dou, Henri J. M. published the artcileS-alkylation in the heterocyclic series by phase transfer catalysis: 2-alkylthiothiazoles, 2-alkylthio-Δ4-thiazolines and 2-alkylthiobenzothiazoles, HPLC of Formula: 5053-24-7, the publication is Helvetica Chimica Acta (1978), 61(8), 3143-8, database is CAplus.
4-Thiazoline-2-thiones, 2-thiazolidinethione, and 2-benzothiazolinethione were S-alkylated with MeI and alkyl bromides under phase transfer catalysis by PhCH2N+Et3 Cl– or Bu4N+ Br– to give 80-90% alkylthio derivatives Similar reaction of 2-bromothiazole with mercaptans gave only low yields of alkylthiothiazoles, accompanied by dequaternization of the catalyst.
Helvetica Chimica Acta published new progress about 5053-24-7. 5053-24-7 belongs to thiazole, auxiliary class Thiazole,sulfides, name is 2-(Methylthio)thiazole, and the molecular formula is C4H5NS2, HPLC of Formula: 5053-24-7.
Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica