Hueller, H. et al. published their research in Pharmazie in 1968 | CAS: 14372-65-7

6-Butoxybenzo[d]thiazol-2-amine (cas: 14372-65-7) belongs to thiazole derivatives. Thiazoles frequently appear in peptide studies. Thiazoles can also be used as protected formyl groups, which can be released in later stages of complex natural product synthesis. Thiazole is a versatile building block for the construction and lead generation of new drug discoveries. Numerous diazole-based compounds are in clinical use as anticancer, antileukemic, antiinflammatory, antiviral, antifungal, antirheumatic, immunomodulator, and antiparasitic agents.Electric Literature of C11H14N2OS

Organic thiocyanogen compounds. XXXII. Fungistatic properties and skin tolerance of some thicyanophenols, thiocyanophenol ethers, and thiocyanophenol ketones was written by Hueller, H.;Luess, K. D.;Wollmann, H.;Pohloudek-Fabini, R.. And the article was included in Pharmazie in 1968.Electric Literature of C11H14N2OS The following contents are mentioned in the article:

Thiocyanophenols, thiocyanophenol ethers, and thiocyanophenol ketones were tested for their fungistatic activity with Candida albicans, Trichophyton mentagrophytes, Epidermophyton floccosum, and Penicillium waksmani. All the thiocyano compounds had stronger fungistatic activity than the corresponding thiocyano free original compounds as in 4-thiocyanophenol vs. phenol, 1-methoxy-2-thiocyanobenzene vs. methoxybenzene, and 4-thiocyanoacetophenone vs. acetophenone. Monothiocyanophenylalkyl ethers and monothiocyanophenylakyl ketones had higher activity than the corresponding dithiocyano compounds Addition of amino group to benzene nucleus of thiocyanophenyl ethers diminished the activity. Healthy skin of guinea pigs and rabbits could tolerate 4-thiocyanophenetole and 4-thiocyanoaceto-phenone up to 1%, 4-thiocyanophenol and 4-thiocyanopropoxybenzene up to 0.1%. Higher concentrations caused reddening and swelling of the skin, and 4-thiocyanopropoxylbenzene at 10% caused necrosis. 12 references. This study involved multiple reactions and reactants, such as 6-Butoxybenzo[d]thiazol-2-amine (cas: 14372-65-7Electric Literature of C11H14N2OS).

6-Butoxybenzo[d]thiazol-2-amine (cas: 14372-65-7) belongs to thiazole derivatives. Thiazoles frequently appear in peptide studies. Thiazoles can also be used as protected formyl groups, which can be released in later stages of complex natural product synthesis. Thiazole is a versatile building block for the construction and lead generation of new drug discoveries. Numerous diazole-based compounds are in clinical use as anticancer, antileukemic, antiinflammatory, antiviral, antifungal, antirheumatic, immunomodulator, and antiparasitic agents.Electric Literature of C11H14N2OS

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica