Lin, Wenyang et al. published their research in Aquaculture in 2020 | CAS: 63208-82-2

2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone Hydrobromide (cas: 63208-82-2) belongs to thiazole derivatives. The higher aromaticity of thiazole is due to delocalization of a lone pair of sulfur electrons across the ring, which is evidenced by chemical shifts of ring hydrogen at δ 7.27 and 8.77 ppm (C2 and C4), indicating diamagnetic ring current. The pyridine-type nitrogen in the thiazole ring deactivates the ring for electrophilic substitution reactions, which is further reduced in acid due to protonation of the thiazole ring.Synthetic Route of C16H19BrN2OS

Large-scale screening of molecules involved in virus-host interaction by specific compounds in Cherax quadricarinatus hematopoietic tissue cells was written by Lin, Wenyang;Guo, Guangran;Zou, Chenchen;Shi, Hong;Ruan, Lingwei. And the article was included in Aquaculture in 2020.Synthetic Route of C16H19BrN2OS The following contents are mentioned in the article:

White spot syndrome virus is one of the major pathogens that seriously threaten crustacean aquaculture. However, knowledge about the mol. mechanism of virus-host interaction remains limited. In the present study, a library containing 303 compounds targeting specific mols. was used for large-scale screening for the first time. Cherax quadricarinatus hematopoietic tissue cells were used in the present study. Combining the anal. of viral infection and cell toxicity test, 30 compounds were demonstrated to be effective. Their targeted mols. were involved in the regulation of a variety of cell signaling pathways and participated in several cellular processes, such as Hedgehog and NF-κB cell signaling pathway and regulation of cellular ions. The present study provides valuable insights into the mol. mechanism of the viral pathogenesis and host immunity, and will help to advance disease control. This study involved multiple reactions and reactants, such as 2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone Hydrobromide (cas: 63208-82-2Synthetic Route of C16H19BrN2OS).

2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone Hydrobromide (cas: 63208-82-2) belongs to thiazole derivatives. The higher aromaticity of thiazole is due to delocalization of a lone pair of sulfur electrons across the ring, which is evidenced by chemical shifts of ring hydrogen at δ 7.27 and 8.77 ppm (C2 and C4), indicating diamagnetic ring current. The pyridine-type nitrogen in the thiazole ring deactivates the ring for electrophilic substitution reactions, which is further reduced in acid due to protonation of the thiazole ring.Synthetic Route of C16H19BrN2OS

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica