Fluorescence-Encoded Infrared Vibrational Spectroscopy with Single-Molecule Sensitivity was written by Whaley-Mayda, Lukas;Guha, Abhirup;Penwell, Samuel B.;Tokmakoff, Andrei. And the article was included in Journal of the American Chemical Society in 2021.Formula: C20H18N2O2S The following contents are mentioned in the article:
Single-mol. methods have revolutionized mol. science, but techniques possessing the structural sensitivity required for chem. problems-e.g. vibrational spectroscopy-remain difficult to apply in solution Here, we describe how coupling IR-vibrational absorption to a fluorescent electronic transition (fluorescence-encoded IR (FEIR) spectroscopy) can achieve single-mol. sensitivity in solution with conventional far-field optics. Using the fluorophore Coumarin 6, we illustrate the principles by which FEIR spectroscopy measures vibrational spectra and relaxation and introduce FEIR correlation spectroscopy, a vibrational analog of fluorescence correlation spectroscopy, to demonstrate single-mol. sensitivity. With further improvements, FEIR spectroscopy could become a powerful tool for single-mol. vibrational investigations in the solution or condensed phase. This study involved multiple reactions and reactants, such as 3-(Benzo[d]thiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one (cas: 38215-36-0Formula: C20H18N2O2S).
3-(Benzo[d]thiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one (cas: 38215-36-0) belongs to thiazole derivatives. Thiazoles frequently appear in peptide studies. Thiazoles can also be used as protected formyl groups, which can be released in later stages of complex natural product synthesis. There are numerous natural products that possess a thiazole ring with broad pharmacological activities. Thiamine, also known as vitamin B1, possesses a thiazole ring linked with 2-methylpyrimidine-4-amine as hydrochloride salt.Formula: C20H18N2O2S
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica