Phoon, C. W.’s team published research in Bioorganic & Medicinal Chemistry Letters in 11 | CAS: 92-36-4

Bioorganic & Medicinal Chemistry Letters published new progress about 92-36-4. 92-36-4 belongs to thiazole, auxiliary class Organic Pigment, name is 2-(4-Aminophenyl)-6-methylbenzothiazole, and the molecular formula is C14H12N2S, Category: thiazole.

Phoon, C. W. published the artcileBiological evaluation of hepatitis C virus helicase inhibitors, Category: thiazole, the publication is Bioorganic & Medicinal Chemistry Letters (2001), 11(13), 1647-1650, database is CAplus and MEDLINE.

A small chem. library has been synthesized and assayed for inhibition of HCV helicase activity. This study provides the structure-activity relationship of the reported inhibitors, with emphasis placed on the aminophenylbenzimidazole moiety and the linkers. Our data highlight the importance of preserving the aminophenylbenzimidazole core and the hydrophobic linkers for biol. activity. The development of a robust HCV helicase assay is also described.

Bioorganic & Medicinal Chemistry Letters published new progress about 92-36-4. 92-36-4 belongs to thiazole, auxiliary class Organic Pigment, name is 2-(4-Aminophenyl)-6-methylbenzothiazole, and the molecular formula is C14H12N2S, Category: thiazole.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica