Acar Cevik, Ulviye published the artcileSynthesis of new benzothiazole derivatives bearing thiadiazole as monoamine oxidase inhibitors, Application of 6-Chlorobenzothiazol-2-ylamine, the publication is Journal of Heterocyclic Chemistry (2020), 57(5), 2225-2233, database is CAplus.
In this study, a novel series of benzothiazole-thiadiazole I (R1 = Et, methoxyethyl, n-Pr, n-Bu; R2 = H, Cl, NO2) was synthesized. These compounds I were evaluated as inhibitors for types A and B MAO enzymes. Compounds I [(A), R1 = methoxyethyl, R2 = NO2; R1 = n-Bu, R2 = NO2, (B)] were the most active derivatives in the series with IC50 values of 0.107 ± 0.003 and 0.128 ± 0.004, resp. Furthermore, compounds (A) and (B) were investigated for their cytotoxicity and found as non-cytotoxic.
Journal of Heterocyclic Chemistry published new progress about 95-24-9. 95-24-9 belongs to thiazole, auxiliary class Organic Pigment, name is 6-Chlorobenzothiazol-2-ylamine, and the molecular formula is C7H5ClN2S, Application of 6-Chlorobenzothiazol-2-ylamine.
Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica