Shaikh, Asif R. published the artcileAntimycobacterial and antimicrobial studies of newly synthesized 3-(4-(6-methylbenzo[d]thiazol-2-yl) phenyl)quinazolin-4(3H)-ones, HPLC of Formula: 92-36-4, the publication is Indian Journal of Research in Pharmacy and Biotechnology (2014), 2(1), 935-942, 8 pp., database is CAplus.
The 7-chloro-2-(substituted)-3-(4-(6-methylbenzo[d]thiazol-2-yl)phenyl) quinazolin-4(3H)-ones e.g., I (R = furan-2-yl) have been prepared from the substituted acids, which were converted to substituted acetyl chlorides and cyclized with 4-chloro anthranilic acid afforded substituted benzoxazines 4(3H)-ones e.g., II and its further reaction with 4-(6-methylbenzo[d]thiazol-2-yl)aniline a gives desired compounds I. In vitro antitubercular activity was carried out against Mycobacterium tuberculosis H37Rv strain using Lowenstein-Jensen medium (conventional method) and antimicrobial activity against various bacteria and fungi using broth microdilution method. The compounds II, I were emerged as promising antimicrobials. It was also observed that the promising antimicrobials have proved to be better antituberculars. The compounds II, I showed better antitubercular activities compared to rifampicin and isoniazid.
Indian Journal of Research in Pharmacy and Biotechnology published new progress about 92-36-4. 92-36-4 belongs to thiazole, auxiliary class Organic Pigment, name is 2-(4-Aminophenyl)-6-methylbenzothiazole, and the molecular formula is C7H6Cl2, HPLC of Formula: 92-36-4.
Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica