van Deurzen, M. P. J. published the artcileChloroperoxidase catalyzed oxidations in t-butyl alcohol/water mixtures, Formula: C4H5NS2, the publication is Journal of Molecular Catalysis A: Chemical (1997), 117(1-3), 329-337, database is CAplus.
A symposium. Chloroperoxidase catalyzed oxidations of sulfides and indoles were performed in tert-Bu alc./water mixtures at ambient temperature tert-Bu alc./water (50:50, volume/volume) proved to be a good solvent system for performing synthetic oxidations catalyzed by chloroperoxidase. The sulfoxidation of alkyl aryl sulfides and related compounds catalyzed by chloroperoxidase in tert-Bu alc./water mixtures (50:50, volume/volume) was compared to the sulfoxidation in water. In both solvent systems, complete enantioselectivity to the R-sulfoxide (ee = 99) was observed with hydrogen peroxide as oxidant when the size of the alkyl moiety was smaller than Pr. The uncatalyzed, racemic sulfoxidation did not proceed under these conditions. This is in contrast to literature data on sulfoxidation in water, where enantioselectivities were lower due to this uncatalyzed reaction. Reactions in water generally proceed faster than reactions in the cosolvent system except for substrates which dissolve poorly in water or for solid substrates for which diffusion becomes an important limiting factor in water. The lower activity in tert-Bu alc./water for sulfoxidation and for indole oxidation is mainly due to an increase of the Km value (thermodynamically controlled). Also a decrease of kcat (catalytic turnover frequency) is observed, probably caused by a change in structure of the enzyme.
Journal of Molecular Catalysis A: Chemical published new progress about 5053-24-7. 5053-24-7 belongs to thiazole, auxiliary class Thiazole,sulfides, name is 2-(Methylthio)thiazole, and the molecular formula is C19H17N2NaO4S, Formula: C4H5NS2.
Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica