Okafor, C. O. published the artcileStudies in the heterocyclic series. XVI. Open azaphenothiazines as new central nervous system depressants, Formula: C6H4ClN3S, the publication is Chemical & Pharmaceutical Bulletin (1982), 30(1), 302-18, database is CAplus and MEDLINE.
Acid-catalyzed condensation of 2-amino-3-mercapto-6-methylpyridine and 3-aminopyridine-2[1H]-thiones with 4-chloropyrimidines having free 5-carbon centers gave N-(3-mercapto-2-pyridyl)-6-pyrimidinylamines (I; R = H2N, MeO, Cl, MeS; R1 = Me, H2N, HO, Cl) and N-(2-thioxo-3-pyridyl)-6-pyrimidinylamines (II; R2 = Cl, MeO), which were described as open 1,3,9-triaza- and 1,3,6-triazaphenothiazines, resp. A newly developed method of reducing nitro groups was used for preparing the aminopyridine precursors. Eight new and five related compounds including an open 1,9-diazaphenoxazine were tested in mice to display central nervous system depressant activities. The most active compound in the series was II (R = R1 = H2N, R2 = Cl). Structure-activity correlations were discussed.
Chemical & Pharmaceutical Bulletin published new progress about 31784-71-1. 31784-71-1 belongs to thiazole, auxiliary class Other Aromatic Heterocyclic,Chloride,Amine, name is 5-Chlorothiazolo[5,4-b]pyridin-2-amine, and the molecular formula is C6H4ClN3S, Formula: C6H4ClN3S.
Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica