Direct transition metal-free C-S bond formation: synthesis of 2-aminobenzothiazole derivatives via base-mediated approach was written by Wang, Rui;Chen, Zhi;Yue, Liang;Pan, Wei;Zhao, Jun-Jie. And the article was included in Tetrahedron Letters in 2012.Name: N-Phenylbenzo[d]thiazol-2-amine This article mentions the following:
A general, efficient, and more practical protocol for the base-mediated intermol. or intramol. S-arylation leading to the 2-aminobenzothiazole derivatives, e.g., I (R1 = H, Me, Meo, F, Cl; R2 = H, Me, Cl, Br, NO2), is reported. Remarkably, all reactions were carried out under transition-metal-free conditions with good to excellent yields, rendering the methodol. presented herein highly valuable from both environmental and economic points of view. In the experiment, the researchers used many compounds, for example, N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6Name: N-Phenylbenzo[d]thiazol-2-amine).
N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6) belongs to thiazole derivatives. The thiazole ring has been identified as a central feature of numerous natural products, perhaps the most famous example of which is epothilone. There are numerous natural products that possess a thiazole ring with broad pharmacological activities. Thiamine, also known as vitamin B1, possesses a thiazole ring linked with 2-methylpyrimidine-4-amine as hydrochloride salt.Name: N-Phenylbenzo[d]thiazol-2-amine
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica