Akhramez, Soufiane et al. published their research in Arabian Journal of Chemistry in 2022 | CAS: 55661-33-1

Thiazol-2-ylmethanamine (cas: 55661-33-1) belongs to thiazole derivatives. The thiazole ring has been identified as a central feature of numerous natural products, perhaps the most famous example of which is epothilone. Thiazole sulfonation occurs only under forcing conditions: the action of oleum at 250 °C for 3 hours in the presence of mercury(II) sulfate leads to 65% formation of 5-thiazole sulfonic acid.Product Details of 55661-33-1

Synthesis of pyrazolo-enaminones, bipyrazoles and pyrazolopyrimidines and evaluation of antioxidant and antimicrobial properties was written by Akhramez, Soufiane;Oumessaoud, Asmaa;Hibot, Achraf;Talbi, Soumaya;Hamri, Salha;Ketatni, El Mostafa;Ouchetto, Hajiba;Hafid, Abderrafia;Ayad, Houda;El Abbadi, Noureddine;Zanane, Chorouk;Latrache, Hassan;Khouili, Mostafa;Pujol, Maria Dolors. And the article was included in Arabian Journal of Chemistry in 2022.Product Details of 55661-33-1 This article mentions the following:

A novel pyrazolo-enaminones I [R = C6H5, 3-Br-C6H4, 4-OCH3-2-NO2-C6H3, etc.], bipyrazoles II [R1 = H, C6H5; R2 = C6H5, 4-CH3C6H4, 4-NO2C6H4, 2,4-NO2C6H3] and pyrazolopyridines e.g., III from 1-(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)butane-1,3-dione and 4-methyl-2-phenyl-2H-pyrazolo[3,4-b]pyridine-3,6(3aH,7H)-dione was synthesized by assisted heating with microwave radiation without any catalyst. The pyridine and pyrazole ring formation had been developed from easily accessible enamino keto esters by formylation followed by intramol. cyclization. The general applicability for the synthesis of the important pyrazolo-enaminones, bipyrazoles and pyrazolo-pyridines heterocycles was attributed to simplicity of operation, synthesis without catalyst, energy efficiency (shorter reaction time under microwave irradiation), good yields, more environmentally friendly and more cost-effective procedure. The antioxidant activity and antibacterial activity of new heterocyclic compounds was evaluated by free radical scavenging by DPPH assay. Several of these compounds showed good activity against both Gram-pos. (S. aureus) and Gram-neg. (E. coli) bacteria. In the experiment, the researchers used many compounds, for example, Thiazol-2-ylmethanamine (cas: 55661-33-1Product Details of 55661-33-1).

Thiazol-2-ylmethanamine (cas: 55661-33-1) belongs to thiazole derivatives. The thiazole ring has been identified as a central feature of numerous natural products, perhaps the most famous example of which is epothilone. Thiazole sulfonation occurs only under forcing conditions: the action of oleum at 250 °C for 3 hours in the presence of mercury(II) sulfate leads to 65% formation of 5-thiazole sulfonic acid.Product Details of 55661-33-1

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica