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The present invention relates to herbicidal heteroaryl-alkyl-oxy-substituted heteroaryl/phenyl-pyridazine-diones and heteroaryl-alkyl-oxy-substituted heteroaryl/phenyl-pyridazinone derivatives of formula (I), as well as to processes and intermediates used for the preparation of such derivatives. The invention further extends to herbicidal compositions comprising such derivatives, as well as to the use of such compounds and compositions in controlling undesirable plant growth; in particular the use in controlling weeds, such as broad-leaved dicotyledonous weeds, in crops of useful plants.

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Thiazole | C3H2859NS – PubChem,
Thiazole | chemical compound | Britannica

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A series of novel 2-substituted aminocycloalkylsulfonamides were designed and synthesized by highly selective N-alkylation reaction, whose structures were characterized by1H NMR,13C NMR and HRMS. Among them, the configuration of compounds III12 and III20 were confirmed by X-ray single crystal diffraction. Bioassays demonstrated that the title compounds had considerable effects on different strains of Botrytis cinerea and Pyricularia grisea. Comparing with positive control procymidone (EC50?=?10.31?mg/L), compounds III28, III29, III30 and III31 showed excellent fungicidal activity against a strain of B. cinerea (CY-09), with EC50values of 3.17, 3.04, 2.54 and 1.99?mg/L respectively. Their in vivo fungicidal activities were also better than the positive controls cyprodinil, procymidone, boscalid and carbendazim in pot experiments. Moreover, the fungicidal activity of III28 (EC50?=?4.62?mg/L) against P. grisea was also better than that of the positive control isoprothiolane (EC50?=?6.11?mg/L). Compound III28 would be great promise as a hit compound for further study based on the structure-activity relationship.

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Thiazole | C3H2970NS – PubChem,
Thiazole | chemical compound | Britannica

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This article describes the process improvements for the preparation of the insecticide clothianidin 1. (Z)-1-Methyl-N-nitro-5-propyl-1,3,5-triazinan-2- imine (9) which was obtained by Mannich reaction of (Z)-1-methyl-2- nitroguanidine (5) n-Propylamine and 37 % aqueous formaldehyde solution in 97 % yield. Intermediate 9 was electrophilic substituted with 2-chloro-5- (chloromethyl)thiazole (4) in the presence of acid-binding agent to give (E)-1-[(2-chlorothiazol-5-yl)methyl]-3-methyl-N-nitro-5-propyl-1,3, 5-triazinan-2-imine (10) in 90 % yield. The target compound 1 was given by the hydrolyzation of 10 in 88 % yield. The optimized conditions for the preparation of clothianidin were obtained via screening the reaction temperature, reaction time, acid-binding and solvents in three steps. The overall yield of clothianidin 1 was up to 77 %.

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Thiazole | C3H2843NS – PubChem,
Thiazole | chemical compound | Britannica

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Application of 105827-91-6, Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.105827-91-6, Name is 2-Chloro-5-(chloromethyl)thiazole, molecular formula is C4H3Cl2NS. In a patent, introducing its new discovery.

Figure represented. A series of novel neonicotinoid analogs containing an amide moiety were synthesized, characterized, and subsequently evaluated for their insecticidal activity. According to the preliminary bioassay, the compounds 6c, 6e, 6f, 6j, 6n, and 6r exhibited > 50% activity against Nilaparvata lugens at 100 mg/L. Amongst the active compounds, 6f and 6r revealed insecticidal activities similar to that displayed by standard buprofezin. J. Heterocyclic Chem., (2011)

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Thiazole | C3H2950NS – PubChem,
Thiazole | chemical compound | Britannica

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The present teachings provide compounds of Formula (I) and pharmaceutically acceptable salts, hydrates, and esters thereof, wherein Ar, R1, R1′, R2, R3, R4 R4′, and p are defined herein. The present teachings also provide processes for producing said compounds and their pharmaceutically acceptable salts, hydrates and esters, and methods of treating a pathological condition or disorder, or alleviating a symptom thereof, using said compounds including their pharmaceutically acceptable salts, hydrates and esters. The compounds can be useful in modulating ion channel activity including treating a variety of conditions associated with the abnormal modulation of one or more voltage-gated calcium channels

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Thiazole | C3H2851NS – PubChem,
Thiazole | chemical compound | Britannica

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Reference of 105827-91-6, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 105827-91-6, Name is 2-Chloro-5-(chloromethyl)thiazole, molecular formula is C4H3Cl2NS. In a Patent£¬once mentioned of 105827-91-6

The present invention relates to the field of the synthesized compounds, in particular to agricultural pesticide of the thiamethoxam synthetic method. The present invention provides a preparation method of thiamethoxam, by selection of appropriate reaction raw materials the design of new synthetic route, can be prepared at room temperature intermediate 2 – chloro – 5 – chloromethyl-thiazole, without the need of cooling equipment, energy saving, and can improve the yield of the reaction. (by machine translation)

The present invention relates to the field of the synthesized compounds, in particular to agricultural pesticide of the thiamethoxam synthetic method. The present invention provides a preparation method of thiamethoxam, by selection of appropriate reaction raw materials the design of new synthetic route, can be prepared at room temperature intermediate 2 – chloro – 5 – chloromethyl-thiazole, without the need of cooling equipment, energy saving, and can improve the yield of the reaction. (by machine translation)

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Reference£º
Thiazole | C3H2854NS – PubChem,
Thiazole | chemical compound | Britannica

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Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Formula: C4H3Cl2NS, you can also check out more blogs about105827-91-6

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.105827-91-6, Name is 2-Chloro-5-(chloromethyl)thiazole, molecular formula is C4H3Cl2NS. In a Patent£¬once mentioned of 105827-91-6, Formula: C4H3Cl2NS

Provided is a method for producing a compound represented by formula (2), or a salt thereof, by reacting ammonia with formaldehyde so as to obtain a mixture that contains a compound represented by formula (8), and then mixing the obtained mixture that contains the compound represented by formula (8) with a compound represented by formula (1), or a salt thereof, in the presence of a base.

Provided is a method for producing a compound represented by formula (2), or a salt thereof, by reacting ammonia with formaldehyde so as to obtain a mixture that contains a compound represented by formula (8), and then mixing the obtained mixture that contains the compound represented by formula (8) with a compound represented by formula (1), or a salt thereof, in the presence of a base.

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Reference£º
Thiazole | C3H2928NS – PubChem,
Thiazole | chemical compound | Britannica

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The invention discloses a 2 – chloro – 5 – chloromethyl-thiazole of the preparation method, comprises the following steps: in the micro-reactor, under solvent-free conditions, chlorine and 1 – isothiocyanate yl – 2 – chloro – 2 – propylene in the composite initiator under the action of the chlorination reaction, to prepare the 2 – chloro – 5 – chloromethyl-thiazole. The method has the solvent is not required, and the cost is low, mild reaction conditions, the reaction speed is fast, less wastes, the process is simple and the target product yield, purity and the like. (by machine translation)

The invention discloses a 2 – chloro – 5 – chloromethyl-thiazole of the preparation method, comprises the following steps: in the micro-reactor, under solvent-free conditions, chlorine and 1 – isothiocyanate yl – 2 – chloro – 2 – propylene in the composite initiator under the action of the chlorination reaction, to prepare the 2 – chloro – 5 – chloromethyl-thiazole. The method has the solvent is not required, and the cost is low, mild reaction conditions, the reaction speed is fast, less wastes, the process is simple and the target product yield, purity and the like. (by machine translation)

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Thiazole | C3H2916NS – PubChem,
Thiazole | chemical compound | Britannica

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The invention discloses a 2 – chloro – 5 – chloromethyl-thiazole of the preparation method, comprises the following steps: in the micro-reactor, under solvent-free conditions, chlorine and 1 – isothiocyanate yl – 2 – chloro – 2 – propylene in the composite initiator under the action of the chlorination reaction, to prepare the 2 – chloro – 5 – chloromethyl-thiazole. The method has the solvent is not required, and the cost is low, mild reaction conditions, the reaction speed is fast, less wastes, the process is simple and the target product yield, purity and the like. (by machine translation)

The invention discloses a 2 – chloro – 5 – chloromethyl-thiazole of the preparation method, comprises the following steps: in the micro-reactor, under solvent-free conditions, chlorine and 1 – isothiocyanate yl – 2 – chloro – 2 – propylene in the composite initiator under the action of the chlorination reaction, to prepare the 2 – chloro – 5 – chloromethyl-thiazole. The method has the solvent is not required, and the cost is low, mild reaction conditions, the reaction speed is fast, less wastes, the process is simple and the target product yield, purity and the like. (by machine translation)

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Reference£º
Thiazole | C3H2916NS – PubChem,
Thiazole | chemical compound | Britannica

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Related Products of 105827-91-6, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 105827-91-6, Name is 2-Chloro-5-(chloromethyl)thiazole, molecular formula is C4H3Cl2NS. In a Article£¬once mentioned of 105827-91-6

A series of cyanonitrovinyl neonicotinoids were designed and synthesized via five steps in about 35% overall yields. All compounds were structurally characterized by 1H nuclear magnetic resonance (NMR), 13C NMR, infrared (IR), and high-resolution mass spectrometry (HRMS), and single-crystal X-ray diffraction analysis of 2-[1-[(6-chloropyridin-3-yl)methyl] -2-imidazolidinylidene]-2-nitroacetonitrile revealed that the double bond is (E)-configured. The preliminary agriculture bioassay indicated that one compound exhibited moderate insecticidal activity against pea aphid. Springer-Verlag 2010.

A series of cyanonitrovinyl neonicotinoids were designed and synthesized via five steps in about 35% overall yields. All compounds were structurally characterized by 1H nuclear magnetic resonance (NMR), 13C NMR, infrared (IR), and high-resolution mass spectrometry (HRMS), and single-crystal X-ray diffraction analysis of 2-[1-[(6-chloropyridin-3-yl)methyl] -2-imidazolidinylidene]-2-nitroacetonitrile revealed that the double bond is (E)-configured. The preliminary agriculture bioassay indicated that one compound exhibited moderate insecticidal activity against pea aphid. Springer-Verlag 2010.

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Reference£º
Thiazole | C3H2975NS – PubChem,
Thiazole | chemical compound | Britannica