Category: 120-75-2

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.120-75-2,2-Methylbenzothiazole,as a common compound, the synthetic route is as follows.

Example 9 (0081) Preparation of Compound (39) (0082) (0083) 2 g of 2-Methyl benzothiazole and 5 g of 1,3-propanesultone in 20 mL chlorobenzene was heated at 120 C. overnight. Then 30 mL ethyl acetate was added, and resulting mixture was refluxed for 30 min. The supernatant was decanted and the residue was dried to give compound 38.

120-75-2, As the paragraph descriping shows that 120-75-2 is playing an increasingly important role.

Reference£º
Patent; Ying, Laiqiang; (24 pag.)US9850382; (2017); B1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.120-75-2,2-Methylbenzothiazole,as a common compound, the synthetic route is as follows.

Synthesis of the intermediate 1-benzyl-2-methylbenzothiazole quaternary ammonium salt. 20 mmol of 2-methylbenzothiazole and 22 mmol of benzyl bromide are added under argon protection into a 50 ml round-bottom flask containing 20 ml toluene, and the reaction mixture is stirred and heated to reflux for 24 hours. After the mixture cools down, the precipitate is filtered and the filter cake is washed with ethyl ether and dried to yield a pale-pink solid powder in a crude yield of 58%., 120-75-2

The synthetic route of 120-75-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.; US2009/17441; (2009); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica