Category: 1239015-83-8

Synergizing palladium with Lewis base catalysis for stereodivergent coupling of 1,3-dienes with pentafluorophenyl acetates was written by Zhang, Qinglong;Zhu, Minghui;Zi, Weiwei. And the article was included in Chem in 2022.Related Products of 1239015-83-8 The following contents are mentioned in the article:

Herein, a synergistic Pd/Lewis-base-catalyzed stereodivergent coupling of 1,3-dienes with pentafluorophenyl acetates was reported. All four stereoisomers of the coupling products was selectively obtained from the same pair of substrates simply by varying the relative chirality of the two catalysts. Coupled with the late-stage transformation of the pentafluorophenyl moiety, this method provided a general method to prepare various chiral mols. bearing vicinal stereocenters. This study involved multiple reactions and reactants, such as (S)-2-Benzyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole (cas: 1239015-83-8Related Products of 1239015-83-8).

(S)-2-Benzyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole (cas: 1239015-83-8) belongs to thiazole derivatives. Thiazoles frequently appear in peptide studies. Thiazoles can also be used as protected formyl groups, which can be released in later stages of complex natural product synthesis. There are numerous natural products that possess a thiazole ring with broad pharmacological activities. Thiamine, also known as vitamin B1, possesses a thiazole ring linked with 2-methylpyrimidine-4-amine as hydrochloride salt.Related Products of 1239015-83-8

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Synthesis of Chiral Esters via Asymmetric Wolff Rearrangement Reaction was written by Meng, Jing;Ding, Wei-Wei;Han, Zhi-Yong. And the article was included in Organic Letters in 2019.Safety of (S)-2-Benzyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole The following contents are mentioned in the article:

The first asym. Wolff rearrangement reaction that directly converts α-diazoketones into broadly useful chiral α,α-disubstituted carboxylic esters with high enantioselectivities (up to 97.5:2.5 er) is reported. The cascade reaction proceeds through the seamless combination of visible-light-induced formation of the ketene intermediate and asym. ketene esterification using a readily available benzotetramisole-type catalyst. This study involved multiple reactions and reactants, such as (S)-2-Benzyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole (cas: 1239015-83-8Safety of (S)-2-Benzyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole).

(S)-2-Benzyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole (cas: 1239015-83-8) belongs to thiazole derivatives. Thiazoles are a class of five-membered rings containing nitrogen and sulfur with excellent antitumor, antiviral and antibiotic activities. Thiazole sulfonation occurs only under forcing conditions: the action of oleum at 250 °C for 3 hours in the presence of mercury(II) sulfate leads to 65% formation of 5-thiazole sulfonic acid.Safety of (S)-2-Benzyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Benzotetramisole catalyzed kinetic resolution of 2H-azirines was written by Peng, Qiupeng;Guo, Donghui;Zhang, Bei;Liu, Lala;Wang, Jian. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020.Electric Literature of C16H14N2S The following contents are mentioned in the article:

An unprecedented benzotetramisole (BTM)-catalyzed kinetic resolution for the efficient synthesis of chiral 2H-azirines is described. This protocol provides two chiral isomers in one step with broad scope, good yield and high enantioselectivity. In addition, the optically pure 2H-azirine products have proven to be useful building blocks for further synthetic transformations. This study involved multiple reactions and reactants, such as (S)-2-Benzyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole (cas: 1239015-83-8Electric Literature of C16H14N2S).

(S)-2-Benzyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole (cas: 1239015-83-8) belongs to thiazole derivatives. The higher aromaticity of thiazole is due to delocalization of a lone pair of sulfur electrons across the ring, which is evidenced by chemical shifts of ring hydrogen at δ 7.27 and 8.77 ppm (C2 and C4), indicating diamagnetic ring current.Various laboratory methods exist for the organic synthesis of thiazoles. For example, 2,4-dimethylthiazole is synthesized from thioacetamide and chloroacetone.Electric Literature of C16H14N2S

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Kinetic Resolution of Racemic α-Arylalkanoic Acids with Achiral Alcohols via the Asymmetric Esterification Using Carboxylic Anhydrides and Acyl-Transfer Catalysts was written by Shiina, Isamu;Nakata, Kenya;Ono, Keisuke;Onda, Yu-suke;Itagaki, Makoto. And the article was included in Journal of the American Chemical Society in 2010.SDS of cas: 1239015-83-8 The following contents are mentioned in the article:

A variety of optically active carboxylic esters are produced by the kinetic resolution of racemic α-substituted carboxylic acids using achiral alcs., aromatic or aliphatic carboxylic anhydrides, and chiral acyl-transfer catalysts. The combination of 4-methoxybenzoic anhydride (PMBA) or pivalic anhydride with the modified benzotetramisole-type catalyst, I, is the most effective for promotion of the enantioselective coupling reaction between racemic carboxylic acids and a novel nucleophile, bis(α-naphthyl)methanol, to give the corresponding esters, e.g. II, with high ee’s. This protocol was successfully applied to the production of nonracemic nonsteroidal anti-inflammatory drugs from racemic compounds utilizing the transacylation process to generate the mixed anhydrides from the acid components with the suitable carboxylic anhydrides. This study involved multiple reactions and reactants, such as (S)-2-Benzyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole (cas: 1239015-83-8SDS of cas: 1239015-83-8).

(S)-2-Benzyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole (cas: 1239015-83-8) belongs to thiazole derivatives. Thiazoles in peptides or their ability to bind proteins, DNA and RNA has led to many synthetic studies and new applications.Various laboratory methods exist for the organic synthesis of thiazoles. For example, 2,4-dimethylthiazole is synthesized from thioacetamide and chloroacetone.SDS of cas: 1239015-83-8

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica