Category: 14779-17-0

14779-17-0, 2-Amino-5-methylbenzothiazole is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A benzene solution of hepta-O-benzo- b-D-lactosylisocyanate (0.001 mol, 1.1g) in 10 ml was mixed withsuspension of 2-amino benzothiazole (0.001 mol,0.15g) in 5 ml and mixture was refluxed over waterbath for 6 hr. Benzene was distilled off and stickymass obtained as a residue was triturated severaltimes with petroleum ether (60-800) to afford a whitesolid. It was crystallized from eq. ethanol.This reaction of 1-hepta-O-benzoyl- b-D-lactosylisocyanate was also extended to several other 2-aminobenzothiazoles and the corresponding 1-hepta-Obenzoyl- b-D-lactosyl-3-(2) benzothiazolyl carbamides(3b-f) have been isolated.3a: IR (KBr): 3449 (-N-H stretch), 3061 (Ar C-H),(Ar C=C), 1269 (C-N), 1174 (C-O), 1101 & 1026(Characteristic of Lactose), 852 (C-S); 1H NMR(CDCl3): 8.16-7.17 (39H, m, ArH), 6.18 (1H, s, NH),6.01 (1H, s, NH), 5.74-4.21 (14H, m, lactosyl protons);Mass : m/z 1245 (M+), 1053, 947, 931, 917, 135,121, 105., 14779-17-0

As the paragraph descriping shows that 14779-17-0 is playing an increasingly important role.

Reference：
Article; Pande, Kedar P.; Ghayalkar, Renu B.; Indian Journal of Heterocyclic Chemistry; vol. 25; 1; (2015); p. 45 – 46;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica

14779-17-0, 2-Amino-5-methylbenzothiazole is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

14 parts of 2-amino-5-methyl-benzothiazole and 11 parts of 1-amino-anthraquinone-2-aldehyde are suspended in 100 parts of N,N-dimethylformamide. 0.2 part of acetic acid is added and the red solution is heated to 140C for 8 hours under nitrogen atmosphere. After cooling to 25C, the suspension is filtered and the cake is washed successively with N,N-dimethylformamide and methanol and then dried. This gives 15 parts of a violet-colored powder., 14779-17-0

As the paragraph descriping shows that 14779-17-0 is playing an increasingly important role.

Reference：
Patent; CLARIANT INTERNATIONAL LTD.; EP1447430; (2004); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.14779-17-0,2-Amino-5-methylbenzothiazole,as a common compound, the synthetic route is as follows.

General procedure: To a solution of 2a,b (5 mmol) in phosphorus oxychloride (10 ml) was added a solution of the appropriate amine (5 mmol) and phosphorus pentoxide (5 mmol) in phosphorus oxychloride (5 ml), and the mixture was refluxed for 5 h. After cooling, the reaction mixture was poured onto ice/water and neutralized with 5% sodium hydroxide solution; the formed precipitate was filtered, washed with water and crystallized from the ethanol.

14779-17-0, The synthetic route of 14779-17-0 has been constantly updated, and we look forward to future research findings.

Reference：
Article; Abbas, Safinaz E.; Abdel Gawad, Nagwa M.; George, Riham F.; Akar, Yahya A.; European Journal of Medicinal Chemistry; vol. 65; (2013); p. 195 – 204;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica

14779-17-0, 2-Amino-5-methylbenzothiazole is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

2, 3 a-Dichloro provided 1, 4 a-napthoquinone 1g (4. 4mmol) diethylether 30 ml a melting solution 2 a-Amino provided 6 a-methylbenzothiazole 1. 08g (6. 6mmol), triethylamine 610 micro l some excellent. 24 hours at room temperature then evaporated in pressure with respect to the stirring mixture. (Hexanes: EtOAc=20:1) column chromatography compound to formula 63 to a positive number (NQ 63) to compound obtained.Yield: 76%

14779-17-0, The synthetic route of 14779-17-0 has been constantly updated, and we look forward to future research findings.

Reference：
Patent; Chosun University Industry-Academic Cooperation Foundation; Cho, Hoon; (48 pag.)KR101761848; (2017); B1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.14779-17-0,2-Amino-5-methylbenzothiazole,as a common compound, the synthetic route is as follows.

3,3-difluoro-2-(phenylethynyl)-3H-indole II-1 (57.0 mg, was added sequentially to a 5 mL reaction flask.0.225 mmol), 5-methylbenzo[d]thiazol-2-amine III-2 (24.6 mg, 0.15 mmol), catalyst TBD (9.8 mg,0.075 mmol) and 1,1,2,2-tetrachloroethane (2.0 mL) were stirred at room temperature for 5 h. The TLC test material has basically been reacted and the reaction is stopped. The reaction solution is directly subjected to column chromatography.Eluent (ethyl acetate / dichloromethane = 1 / 20),Yellow solid product I-9 (47.5 mg) was obtained with a yield of 76%.

14779-17-0, 14779-17-0 2-Amino-5-methylbenzothiazole 26889, athiazole compound, is more and more widely used in various fields.

Reference：
Patent; Guangzhou University; Liu Yunlin; Lin Xiaotong; Mao Xiangyu; Chen Guoshu; (15 pag.)CN108586495; (2018); A;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica

14779-17-0, 2-Amino-5-methylbenzothiazole is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: To a solution of 2a,b (5 mmol) in phosphorus oxychloride (10 ml) was added a solution of the appropriate amine (5 mmol) and phosphorus pentoxide (5 mmol) in phosphorus oxychloride (5 ml), and the mixture was refluxed for 5 h. After cooling, the reaction mixture was poured onto ice/water and neutralized with 5% sodium hydroxide solution; the formed precipitate was filtered, washed with water and crystallized from the ethanol., 14779-17-0

14779-17-0 2-Amino-5-methylbenzothiazole 26889, athiazole compound, is more and more widely used in various fields.

Reference：
Article; Abbas, Safinaz E.; Abdel Gawad, Nagwa M.; George, Riham F.; Akar, Yahya A.; European Journal of Medicinal Chemistry; vol. 65; (2013); p. 195 – 204;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.14779-17-0,2-Amino-5-methylbenzothiazole,as a common compound, the synthetic route is as follows.

General procedure: To a 10 mL round bottom flask was added 0.5 mmolof the amine and 0.1 mL of acetic anhydride. The reactionis instantaneous and exothermic, and after 10 s the solidproduct formed was filtered and washed with cold water.When no solid was immediately formed, 4 mL of coldwater was added, and the mixture allowed standing ina refrigerator for 24 h, leading to precipitation. To allsynthesized acetamides, measured physical data were inagreement to the reported values.17-19,27,31,32

14779-17-0, As the paragraph descriping shows that 14779-17-0 is playing an increasingly important role.

Reference：
Article; Cunha, Silvio; De Santana, Lourenco L. B.; Journal of the Brazilian Chemical Society; vol. 28; 6; (2017); p. 1137 – 1144;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica