Category: 1603-91-4

Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 1603-91-4, Name is 4-Methylthiazol-2-amine, molecular formula is C4H6N2S. In a Patent, authors is LAMA, Juan£¬once mentioned of 1603-91-4, 1603-91-4

The invention disclosed herein are embodiments of compounds capable of treating a viral infection. For example, the compounds are capable of inhibiting viral downmodulation of major histocompatibility complex I (MHC-I), such as by acting as immunomodulators of the immune system to treat, cure or eradicate a viral infection (e.g., HIV infection). More particularly, the present disclosure relates to the use of a heteroaryl compound or salts or analogs thereof, in the treatment of patients infected with a virus. The disclosed compounds may be used alone or in combination with other pharmacologically active agents to treat, cure or eradicate the virus, particularly in patients with persistent, latent viral infection. In some embodiments, the disclosed compounds can be used alone or in combination with other pharmacologically active agents to promote reactivation of viral production in latent cells and eradication of such cells.

The invention disclosed herein are embodiments of compounds capable of treating a viral infection. For example, the compounds are capable of inhibiting viral downmodulation of major histocompatibility complex I (MHC-I), such as by acting as immunomodulators of the immune system to treat, cure or eradicate a viral infection (e.g., HIV infection). More particularly, the present disclosure relates to the use of a heteroaryl compound or salts or analogs thereof, in the treatment of patients infected with a virus. The disclosed compounds may be used alone or in combination with other pharmacologically active agents to treat, cure or eradicate the virus, particularly in patients with persistent, latent viral infection. In some embodiments, the disclosed compounds can be used alone or in combination with other pharmacologically active agents to promote reactivation of viral production in latent cells and eradication of such cells.

1603-91-4, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 1603-91-4

Reference£º
Thiazole | C3H9686NS – PubChem,
Thiazole | chemical compound | Britannica

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1603-91-4,4-Methylthiazol-2-amine,as a common compound, the synthetic route is as follows.

Mix 3-bromoacetophenone (0.6 mmol, 119 mg) and p-toluenesulfonyl hydrazide (0.6 mmol, 112 mg) in toluene (10 mL), and react at 40 oC for 2 hours.Then add 2-amino-4-methylthiazole (0.4 mmol, 46 mg), Cu (NO3) 2 ¡¤ 3H2O (16 mg), and lithium t-butoxide (96 mg) to the above reaction system at 100 oC The reaction was continued for 3 hours. After the TLC detection reaction was completed, dichloromethane was added to the system, successively washed with brine and water, dried over anhydrous sodium sulfate, concentrated under reduced pressure, and separated by column chromatography to obtain the final pure compound 3t (80%, 95.1 mg)., 1603-91-4

As the paragraph descriping shows that 1603-91-4 is playing an increasingly important role.

Reference£º
Patent; Jining Medical University; Xie Zengyang; Liu Jun; Yang Qianqian; Zhang Bo; (15 pag.)CN110229121; (2019); A;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica

1603-91-4, 4-Methylthiazol-2-amine is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Example 45Synthesis of (4-methyl-thiazol-2-yl)-carbamic acid tert-butyl ester (VIl-I) To a round bottom flask containing 40 mL CH2Cl2 was added I (695 mg, 6.09 mmol), 4-DMAP (52.3 mg, 0.43 mmol), and BoC2O (1.374 g, 6.29 mmol). The reaction mixture was stirred overnight at room temperature. Concentration of the solution in vacuo was followed by purification by column chromatography (silica gel, hexanes:EtOAc, 10: 1), affording the product as white crystals (54%).

1603-91-4, The synthetic route of 1603-91-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; NORTHWESTERN UNIVERSITY; SILVERMAN, Richard, B.; JI, Haitao; LAWTON, Graham, R.; WO2008/42353; (2008); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1603-91-4,4-Methylthiazol-2-amine,as a common compound, the synthetic route is as follows.

To a round bottom flask containing 40 mL CHUCK was added I (695 mg, 6.09 mmol), 4-DMAP (52.3 MG, 0.43 mmol), and BOC20 (1.374 g, 6.29 mmol). The reaction mixture was stirred overnight at room temperature. Concentration of the solution in vacuo was followed by purification by column chromatography (silica gel, hexanes: EtOAc, 10: 1), affording the product as white crystals (54 %)., 1603-91-4

As the paragraph descriping shows that 1603-91-4 is playing an increasingly important role.

Reference£º
Patent; NORTHWESTERN UNIVERSITY; WO2005/26111; (2005); A2;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica

1603-91-4, 4-Methylthiazol-2-amine is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: A mixture of appropriate 2-substituent-1H-benzimidazole-4-carboxylic acid (1 mmol), EDC¡¤HCl (0.29 g, 1.5 mmol), HOBt (0.20 g, 1.5 mmol) and Et3N (0.15 g, 1.5 mmol) in DMF (10 mL) was stirred for 1 h at 0 C. Then appropriate amine (1.05 mmol) was added to the solution. The solution was heated up to 25 C, stirred for 12 h and then evaporated to dryness. The solid was washed with water and dried. The products were purified on silica gel column using 10:1 ethyl acetate/ethanol.

1603-91-4, 1603-91-4 4-Methylthiazol-2-amine 74143, athiazole compound, is more and more widely used in various fields.

Reference£º
Article; Xue, Fei; Luo, Xianjin; Ye, Chenghao; Ye, Weidong; Wang, Yue; Bioorganic and Medicinal Chemistry; vol. 19; 8; (2011); p. 2641 – 2649;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica