Category: 19759-66-1

Synthetic Route of 19759-66-1, An article , which mentions 19759-66-1, molecular formula is C8H5N3S. The compound – 2-Aminobenzothiazole-6-carbonitrile played an important role in people’s production and life.

Acyl derivatives of 2-aminobenzothiazole and alkylated analogs thereof as antitumor agents.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 19759-66-1, help many people in the next few years., Synthetic Route of 19759-66-1

Reference：
Thiazole | C3H2259NS – PubChem,
Thiazole | chemical compound | Britannica

Synthetic Route of 19759-66-1, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 19759-66-1, C8H5N3S. A document type is Article, introducing its new discovery.

(Equation Presented). A simple and straightforward method has been developed for the direct carboxylation of aromatic heterocylces such as oxazoles, thiazoles, and oxadiazoles using CO2 as the C1 source. The reactions require no metal catalyst and only Cs2CO3 as the base. A good functional group tolerance is achieved.

If you are hungry for even more, make sure to check my other article about 19759-66-1. Application of 19759-66-1

Reference：
Thiazole | C3H2273NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 19759-66-1, Name is 2-Aminobenzothiazole-6-carbonitrile, molecular formula is C8H5N3S. In a Patent，once mentioned of 19759-66-1, SDS of cas: 19759-66-1

The invention discloses substituted aromatic amine compounds which are shown in a general formula I as described in the specification. Each substituent in the general formula I is defined in the specification. The compounds as shown in the general formula I have excellent bactericidal activity and can be used for preparing medicines used for preventing and treating bacteria in agriculture, forestry or the health care industry.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.SDS of cas: 19759-66-1. In my other articles, you can also check out more blogs about 19759-66-1

Reference：
Thiazole | C3H2241NS – PubChem,
Thiazole | chemical compound | Britannica

In an article, published in an article, once mentioned the application of 19759-66-1, Name is 2-Aminobenzothiazole-6-carbonitrile,molecular formula is C8H5N3S, is a conventional compound. this article was the specific content is as follows.SDS of cas: 19759-66-1

Provided are compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, X, Z1, Z2, Z3, Z4 and m are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula I, or a pharmaceutically acceptable salt thereof.

Do you like my blog? If you like, you can also browse other articles about this kind. SDS of cas: 19759-66-1. Thanks for taking the time to read the blog about 19759-66-1

Reference：
Thiazole | C3H2244NS – PubChem,
Thiazole | chemical compound | Britannica

In an article, published in an article, once mentioned the application of 19759-66-1, Name is 2-Aminobenzothiazole-6-carbonitrile,molecular formula is C8H5N3S, is a conventional compound. this article was the specific content is as follows.SDS of cas: 19759-66-1

Provided are compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, X, Z1, Z2, Z3, Z4 and m are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula I, or a pharmaceutically acceptable salt thereof.

Do you like my blog? If you like, you can also browse other articles about this kind. SDS of cas: 19759-66-1. Thanks for taking the time to read the blog about 19759-66-1

Reference：
Thiazole | C3H2244NS – PubChem,
Thiazole | chemical compound | Britannica

19759-66-1, Name is 2-Aminobenzothiazole-6-carbonitrile, molecular formula is C8H5N3S, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 19759-66-1, Product Details of 19759-66-1

In order to generate hybrid antimicrobial remedies with novel mode of action, two series of quinoline based 1,3,4-oxadiazole derivatives condensed with N-aryl/benzothiazolyl acetamides were synthesized and the MIC values of the compounds towards eight reference bacterial strains (S. aureus, B. cereus, E. coli, P. aeruginosa, K. pneumoniae, S. typhi, P. vulgaris, S. flexneri), four fungi (A. niger, A. fumigatus, A. clavatus, C. albicans) and Mycobacterium tuberculosis H37Rv were assayed in vitro. Quinoline-6-carboxlic acid was treated with thionyl chloride in refluxing methanol to obtain the corresponding ester derivative to be hydrazinolyzed by 99% hydrazine hydrate in ethanol to produce carbohydrazide intermediate. The carbohydrazide precursor underwent cyclization by carbon disulfide and ethanolic KOH to construct 5-quinolinyl-6-yl-1,3,4- oxadiazol-2-thiol. Substituted 2-chloro-N-phenyl(benzothiazolyl)aceta-mide derivatives were then condensed to 1,3,4-oxadiazole nucleus via sulphur linkage to yield the desired products. Target products bearing N-benzothiazolyl-2- chloroacetamides displayed good inhibitory potential. The biological screening identified that many final analogues exhibited a significant inhibition of the growth of microorganisms at 3.12-25 mug/mL of MIC, which were comparable to control drugs. The influence of the presence of various functional groups to the phenyl/benzothiazolyl ring on activity profiles was investigated. The proposed structures of the newly prepared products were confirmed with the aid of IR, 1H NMR, 13C NMR spectroscopy and elemental analysis. These results may provide new insights in the design of a novel pool of bioactive templates.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Product Details of 19759-66-1. In my other articles, you can also check out more blogs about 19759-66-1

Reference：
Thiazole | C3H2249NS – PubChem,
Thiazole | chemical compound | Britannica

Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 19759-66-1, C8H5N3S. A document type is Article, introducing its new discovery., Product Details of 19759-66-1

Novel FabK inhibitors with antibacterial activity against Streptococcus pneumoniae were synthesized and evaluated. Through SAR studies of our initial hit compound 2-(1H-benz[d]imidazol-2-ylthio)-N-(6-methoxycarbonylbenzo[d]thiazol-2-yl)acetamide, a series of novel phenylimidazole derivatives were discovered as potent FabK inhibitors.

Interested yet? Keep reading other articles of 19759-66-1!, Product Details of 19759-66-1

Reference：
Thiazole | C3H2245NS – PubChem,
Thiazole | chemical compound | Britannica

Reference of 19759-66-1, An article , which mentions 19759-66-1, molecular formula is C8H5N3S. The compound – 2-Aminobenzothiazole-6-carbonitrile played an important role in people’s production and life.

A series of 1,3-benzothiazoles (series I) and 4,5,6,7-tetrahydro-1,3-benzothiazoles (series II) bearing an urea or a thiourea moiety at the 2-position were synthesized and tested as myorelaxants and inhibitors of insulin secretion. Several compounds (i.e. 13u and 13v) from series I showed a marked myorelaxant activity. Benzothiazoles bearing a strong electron withdrawing group (NO2, CN) at the 6-position and an alkyl group linked to the urea or the thiourea function at the 2-position were found to be the most potent compounds. The weak vasorelaxant activity of series II compounds evidenced the necessity of the presence of a complete aromatic heterocyclic system. The myorelaxant activity of some active compounds was reduced when measured on aorta rings precontracted by 80 mM KCl or by 30 mM KCl in the presence of 10 muM glibenclamide, suggesting the involvement of KATP channels in the vasorelaxant effect. Some compounds of series I tested on rat pancreatic islets provoked a marked inhibition of insulin secretion, among which 13a exhibited a clear tissue selectivity for pancreatic beta-cells.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 19759-66-1, help many people in the next few years., Reference of 19759-66-1

Reference：
Thiazole | C3H2264NS – PubChem,
Thiazole | chemical compound | Britannica

Synthetic Route of 19759-66-1. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 19759-66-1, Name is 2-Aminobenzothiazole-6-carbonitrile

7-(4-Bromobutoxy)-5-hydroxy-2-phenyl-4H-chromen-4-one, obtained from chrysin with 1,4-dibromobutane, was combined with a wide range of 6-substituted 2-aminobenzthiazoles, which had been prepared from the corresponding anilines with potassium thiocyanate. Free radical scavenging efficacies of newer analogues were measured using DPPH and ABTS assays, in addition to the assessment of their anticancer activity against cervical cancer cell lines (HeLa and CaSki) and ovarian cancer cell line (SK-OV-3) implementing the SRB assay. Cytotoxicity of titled compounds was checked using Madin-Darby canine kidney (MDCK) non-cancer cell line. Overall, 6a-r indicated remarkable antioxidant power as DPPH and ABTS+ scavengers; particularly the presence of halogen(s) (6g, 6h, 6j-6l) was favourable with IC50 values comparable to the control ascorbic acid. Unsubstituted benzothiazole ring favored the activity of resultant compounds (6a and 6r) against HeLa cell line, whereas presence of chlorine (6g) or a di-fluoro group (6k) was a key to exert strong action against CaSki. Moreover, a mono-fluoro (6j) and a ketonic functionality (6o) were beneficial to display anticipated anticancer effects against ovarian cancer cell line SK-OV-3. The structural assignments of the new products were done on the basis of IR, 1H NMR, 13C NMR spectroscopy and elemental analysis.

If you are hungry for even more, make sure to check my other article about 19759-66-1. Synthetic Route of 19759-66-1

Reference：
Thiazole | C3H2271NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.19759-66-1, Name is 2-Aminobenzothiazole-6-carbonitrile, molecular formula is C8H5N3S. In a Patent，once mentioned of 19759-66-1, COA of Formula: C8H5N3S

A disperse dye of the formula, STR1 wherein R1 is an alkyl group having 5 to 6 carbon atoms, R2 is an alkyl group having 5 to 6 carbon atoms, a cyano-ethyl group, R3 is a hydrogen atom or a lower alkyl, amino or phenyl group, and Y1 and Y2 represent independently a hydrogen atom, a lower alkyl group, a lower alkoxy group, a halogen atom, a nitro group, a cyano group, a thiocyanate group or an alkylsulfonyl group, provided that both Y1 and Y2 are not hydrogen at the same time and Y1 is located at the 4- or 5-position, which is useful for dyeing hydrophobic fibers in brilliant red to violet shade with good fastnesses.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.COA of Formula: C8H5N3S, you can also check out more blogs about19759-66-1

Reference：
Thiazole | C3H2269NS – PubChem,
Thiazole | chemical compound | Britannica