Category: 2010-06-2

Kakati, Praachi; Singh, Preeti; Yadav, Priyanka; Awasthi, Satish Kumar published an article in 2021, the title of the article was Aiding the versatility of simple ammonium ionic liquids by the synthesis of bioactive 1,2,3,4-tetrahydropyrimidine, 2-aminothiazole and quinazolinone derivatives.Recommanded Product: 2010-06-2 And the article contains the following content:

Simple ammonium ionic liquids [ILs] are efficient, green, environmentally friendly catalysts in promoting the Biginelli condensation reaction, Hantzsch reaction and Niementowski reaction to afford 1,2,3,4-tetrahydropyrimidine, 2-aminothiazole and quinazolinone derivatives resp. by eliminating the need for harmful volatile organic solvents. These [ILs] are air and water stable, easy to prepare and cost-effective. The effects of the anions and cations present in [IL] on reactions were investigated. The results clearly indicated that the Biginelli condensation reaction, Hantzsch reaction and Niementowski reaction were heavily influenced by the acidity of [IL], and among various ammonium ionic liquids, [Et3NH][HSO4] showed the best catalytic activity. Furthermore, [IL] could be easily separated and reused with a slight loss of its activity. This technique provided a good alternative way for the industrial synthesis of 1,2,3,4-tetrahydropyrimidinones, 2-aminothiazoles and quinazolinones. The present processes are eco-friendly methods for the synthesis of these derivatives authenticated by several green parameters, namely, E-factor, process mass intensity, reaction mass efficiency, atom economy, and carbon efficiency. The experimental process involved the reaction of 4-Phenylthiazol-2-amine(cas: 2010-06-2).Recommanded Product: 2010-06-2

The Article related to tetrahydropyrimidine aminothiazole quinazolinone preparation green chem ionic liquid, thiourea urea ethyl acetoacetate benzaldehyde biginelli condensation, acetophenone thiourea hantzsch reaction, isatoic anhydride aniline triethylorthoformate niementowski reaction and other aspects.Recommanded Product: 2010-06-2

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Butta, Ragavendra; Ummadi, Nagarjuna; Adivireddy, Padmaja; Venkatapuram, Padmavathi published an article in 2019, the title of the article was Synthesis and antimicrobial activity of pyrimidinylsulfamoyl azolylbenzamides.SDS of cas: 2010-06-2 And the article contains the following content:

A variety of sulfonamide linked azolyl pyrimidines I [R = H, Cl, Br, Me, NO2; X = O, S, NH] were prepared and studied for their antimicrobial activity. The chloro and nitro substituted thiazolyl pyrimidines I [R = Cl, NO2; X = S] displayed potential antibacterial activity against Bacillus subtilis. The chloro, bromo and nitro substituted imidazolyl pyrimidines I [R = Cl, Br, NO2; X = NH] showed potential antifungal activity against A. niger. The experimental process involved the reaction of 4-Phenylthiazol-2-amine(cas: 2010-06-2).SDS of cas: 2010-06-2

The Article related to diaryl pyrimidinylsulfamoyl aryloxazolyl benzamide preparation antibacterial antifungal, preparation diaryl pyrimidinylsulfamoyl arylthiazolyl benzamide antibacterial antifungal, antibacterial antifungal diaryl pyrimidinylsulfamoyl arylimidazolyl benzamide preparation and other aspects.SDS of cas: 2010-06-2

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica