Category: 2010-06-2

On July 31, 2019, Farahati, Razieh; Ghaffarinejad, Ali; Mousavi-Khoshdel, S. Morteza; Rezania, Jafar; Behzadi, Hadi; Shockravi, Abbas published an article.Application In Synthesis of 4-Phenylthiazol-2-amine The title of the article was Synthesis and potential applications of some thiazoles as corrosion inhibitor of copper in 1 M HCl: Experimental and theoretical studies. And the article contained the following:

Thiazoles continue to attend in synthetic organic chem. due to their wide applications in the development of corrosion inhibitors. This study presents synthesis and corrosion inhibition ability of three thiazoles-4-(2-aminothiazole-4-yl) phenol (ATP), 4-phenylthiazole-2-amine (PTA) and 4,4′-(thiobis(2-aminothiazole-5,4-diyl)) diphenol (TATD) on the copper surface, where TATD is a dimer form of ATP. The inhibition efficiencies were evaluated by potentiodynamic polarization, electrochem. impedance spectroscopy (EIS), at. force microscopy (AFM) and SEM (SEM) in various concentrations of thiazoles containing 1 M HCl solution Computational studies (d. functional theory (DFT) and mol. dynamics (MD) simulation) were also performed. The corrosion inhibition efficiencies of these compounds at optimum concentration were about 90%, indicating that ATP, PTA and TATD could be employed as effective corrosion inhibitors. Comparing the corrosion inhibition efficiencies of monomer ATP and dimer form TATD of thiazole also indicated that dimerization of inhibitor did not cause better interaction with the copper surface and more efficiency. The adsorption of inhibitors could be successfully described by the Langmuir adsorption isotherm. The experimental process involved the reaction of 4-Phenylthiazol-2-amine(cas: 2010-06-2).Application In Synthesis of 4-Phenylthiazol-2-amine

The Article related to phenylthiazole copper adsorption potential energy corrosion inhibition ir spectra, Physical Organic Chemistry: Other Reactions, Processes, and Spectra and other aspects.Application In Synthesis of 4-Phenylthiazol-2-amine

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

On December 5, 2022, Odey, Joseph O.; Ubana, Emmanuel I.; Eko, Ishegbe J.; Jones, Okama O. published an article.Electric Literature of 2010-06-2 The title of the article was Synthesis, characterization and theoretical studies of the photovoltaic properties of novel bifunctional reactive disperse dyes based on aminothiazole derivatives. And the article contained the following:

This article comprises synthesis and characterization of two polyfunctional diazo reactive-disperse dyes with aminothiazole moiety for application in dye-sensitized solar cells (DSSC). The characterization techniques employed were Gas chromatog.-mass spectrometry (GC-MS), Fourier-transform IR spectroscopy (FT-IR), UV-visible spectroscopy (UV-vis), and NMR to determine the different functional groups, mol. connectivities and mol. weight of the various fragments of the synthesized dyes. Theor. D. Functional Theory (DFT) and Time-Dependent TD-DFT calculations were performed using B3LYP/6-311+g(d,p). It can be observed that the HOMO energy levels of the resp. dyes have lower values than I-/I3- redox couple level (around -4.80 eV) in the four different phases studied, which is crucial for the regeneration of the oxidized dye mol. and efficient charge separation Furthermore, the HOMO-LUMO energy gaps of DYES F and S are within the range 2.38-5.40 eV, where all LUMO-CB of TiO2 energy gap values are sufficient for generating enough driving force for effective electron injection. The promising results of Light-harvesting efficiency (LHE) (values ranging from 0.81 to 0.89 except for DYE S in chloroform phase where it has an unusual value of 0.21) and Open-circuit voltage (VOC) values gotten compared with other organic, and natural sensitizers were due to the better interaction between the carboxyl and carbonyl groups of aryl azo mol. joined to the thiazolyl nucleus and the surface of TiO2 permeable film. DYE S exhibits the lowest band gap (2.374eV), which designates the highest chem. activity of the two dyes. Results from the quantum theory of atoms-in-mols. indicate that DYES F and S exhibit addnl. stability due to their relatively high H-bond interactions as well as certain addnl. intra-at. bonds among the atoms of the investigated compounds The outcome of the Natural bond orbital (NBO) anal. suggests that the strongest charge transfer occurs in DYE S as compared to DYE F. The types and modes of excitations for the first five excited states of the synthesized dyes were observed from the results of the hole-electron excitation anal. First hyperpolarizability values of the dye F and dye S were determined to be 47.24 and 46.90 times the hyperpolarizability value of urea, demonstrating its excellent non-linear optical (NLO) response. The experimental process involved the reaction of 4-Phenylthiazol-2-amine(cas: 2010-06-2).Electric Literature of 2010-06-2

The Article related to bifunctional aminothiazole dye preparation dssc electron transfer nlo, Physical Organic Chemistry: Other Reactions, Processes, and Spectra and other aspects.Electric Literature of 2010-06-2

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Ghabbour, Hazem A.; Fahim, Asmaa M.; Abu El-Enin, Mohammed A.; Al-Rashood, Sara T.; Abdel-Aziz, Hatem A. published an article in 2022, the title of the article was Crystal structure, Hirshfeld surface analysis and computational study of three 2-(4-arylthiazol-2-yl)isoindoline-1,3-dione derivatives.COA of Formula: C9H8N2S And the article contains the following content:

In these studies, we investigated the importance of isoindoline in pharmacol. evaluation, so we studied the crystal structure, packing, Hirshfeld anal. and computational calculations of 2-(4-arylthiazol-2-yl)isoindoline-1,3-dione derivatives . All single crystal structures of these isoindoline-1,3-dione were shown monoclinic system; P21/n space group and their net diploe moment 2.20, 3.73, 2.02 Debye, resp. Furthermore, Hirshfeld surface anal. was useful technique for visualization and analyze the intermol. interaction between atoms in mol., therefore, the isoindoline derivatives showed different contacts were mostly in H….H range (24.4%-36.5%), H range (8.7%-121.1%), S….H range (4.5%-5.6%) and C….H range (5.4%-10.6%); resp. The isoindoline 4c showed higher intermol. interaction dur to presence of two OCH3 groups. These single crystal structures of dione derivatives were comparable with theor. studies utilized DFT/6-311(G)d,p basis set and determination their phys. descriptors, MEP, HOMO-LUMO band energy gap and charge distribution. Moreover, the correlation studies of the 1HNMR spectral anal. between exptl. and theor. and they were excellent fitted with each other’s. The experimental process involved the reaction of 4-Phenylthiazol-2-amine(cas: 2010-06-2).COA of Formula: C9H8N2S

The Article related to arylthiazole iosindolinedione crystal structure homo lumo nmr chem shift, Physical Organic Chemistry: Other Reactions, Processes, and Spectra and other aspects.COA of Formula: C9H8N2S

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

On February 28, 2022, Kalhor, Mehdi; Zarnegar, Zohre published an article.Quality Control of 4-Phenylthiazol-2-amine The title of the article was 1-Methylimidazolium ionic liquid supported on Ni@zeolite-Y: fabrication and performance as a novel multi-functional nanocatalyst for one-pot synthesis of 2-aminothiazoles and 2-aryl benzimidazoles. And the article contained the following:

In the present study, 1-methyl-3-(3-trimethoxysilylpropyl)-1H-imidazol-3-ium chloride-supported Ni@zeolite-Y-based nanoporous materials (Ni@zeolite-Im-IL) were synthesized and their structures were confirmed using different characterization techniques such as FT-IR, FE-SEM, EDX, XRD, BET and TGA-DTG analyses. In order to synthesize this multi-functional nano-system, zeolite-NaY was modified first, with exchanged Ni2+ ions and 3-chloropropyltriethoxysilane (CPTES) as a coupling reagent and then functionalized to imidazolium chloride ionic liquid by N-methylimidazole. New multi-functional nano-material of Ni@zeolite-Im-IL demonstrated high activity in the catalytic synthesis of 2-aminothiazoles 3a-l by one-pot reaction of methylcarbonyls, thiourea and iodine at 80°C in DMSO with good to excellent yields (85-98%). Also, the catalytic synthesis of 2-aryl benzimidazoles, 6a-m was performed by the condensational reaction of o-arylendiamine and aromatic aldehydes in EtOH at room temperature with excellent yields (90-98%). Advantages of this efficient synthetic strategy include higher purity and shorter reaction time, excellent yield, easy isolation of products, the good stability, activity and feasible reusability of the metallic ionic liquid nanocatalyst. These benefits have made this method more compatible with the principles of green chem. The experimental process involved the reaction of 4-Phenylthiazol-2-amine(cas: 2010-06-2).Quality Control of 4-Phenylthiazol-2-amine

The Article related to methylimidazolium ionic liquid supported nickel zeolitey nanocatalyst synthesis fabrication, Catalysis, Reaction Kinetics, and Inorganic Reaction Mechanisms: Catalysts and other aspects.Quality Control of 4-Phenylthiazol-2-amine

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

On November 26, 2021, Sadgar, Amid L.; Deore, Tushar S.; Hase, Dattatraya V.; Jayaram, Radha V. published an article.Electric Literature of 2010-06-2 The title of the article was Graphene Oxide Pickering Emulsion – A Novel Reaction Medium for the Synthesis of 2-Aminothiazole. And the article contained the following:

In the present study, a novel protocol for the synthesis of 2-aminothiazoles was developed using a graphene oxide (GO) stabilized pickering emulsion system. GO was prepared by the modified Hummer’s method and characterized with XRD, FTIR, UV-Visible spectroscopy, TGA and DLS techniques. The size of the o/w emulsion droplets stabilized by GO were determined using a polarized optical microscope. The emulsion system was used for the synthesis of 2-aminothiazole by Hantzsch reaction. The Reactions were carried out at room temperature and under static condition, without stirring. The application of the reaction system were extended to substituted phenacyl bromides and about 93% of the corresponding 2-aminothiazole derivative was obtained in 3 h. The experimental process involved the reaction of 4-Phenylthiazol-2-amine(cas: 2010-06-2).Electric Literature of 2010-06-2

The Article related to graphene oxide catalyst preparation, aminothiazole preparation, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Electric Literature of 2010-06-2

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

On June 30, 2020, Ikram, Sadaf; Dsoke, Sonia; Sarapulova, Angelina; Mueller, Marcus; Rana, Usman Ali; Siddiqi, Humaira M. published an article.Electric Literature of 2010-06-2 The title of the article was Investigation of N and S Co-doped porous carbon for sodium-ion battery, synthesized by using ammonium sulphate for simultaneous activation and heteroatom doping. And the article contained the following:

In the present work, nitrogen and sulfur co-doped porous carbon materials are obtained by using ammonium sulfate as a template. The multi-role of ammonium sulfate as an activating agent and as nitrogen and sulfur dopant is investigated. The resulting porous carbon material achieved high doping level (9.3 at% for nitrogen and 3.5 at% for sulfur) and increased interlayer spacing from 0.35 to 0.38 nm which improves the storage kinetics of Na+-ions inside the carbon lattice. The synthesized materials, when used as neg. electrodes for sodium-ion battery, provide promising electrochem. performance with a reversible storage capacity of 439 mAh g-1 at a c.d. of 10 mA g-1. The storage capacity of ~100 mAh g-1 with capacity retention of 62% retained after 200 cycles at 220 mA g-1. This work presents the multifunctional roles of ammonium sulfate in achieving the nitrogen and sulfur co-doped porous carbon materials. The experimental process involved the reaction of 4-Phenylthiazol-2-amine(cas: 2010-06-2).Electric Literature of 2010-06-2

The Article related to nitrogen sulfur porous carbon ammonium sulfate sodium ion battery, Electrochemical, Radiational, and Thermal Energy Technology: Energy Sources and other aspects.Electric Literature of 2010-06-2

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

On March 28, 2019, Dai, Weiyang; Samanta, Soma; Xue, Ding; Petrunak, Elyse M.; Stuckey, Jeanne A.; Han, Yanyan; Sun, Duxin; Wu, Yong; Neamati, Nouri published an article.Computed Properties of 2010-06-2 The title of the article was Structure-Based Design of N-(5-Phenylthiazol-2-yl)acrylamides as Novel and Potent Glutathione S-Transferase Omega 1 Inhibitors. And the article contained the following:

Using reported glutathione S-transferase omega 1 (GSTO1-1) cocrystal structures, we designed and synthesized acrylamide-containing compounds that covalently bind to Cys32 on the catalytic site. Starting from a thiazole derivative I (X = H, GSTO1-1 IC50 = 0.6 μM), compound I (X = Cl) was synthesized and cocrystd. with GSTO1. Modification on the amide moiety of hit compound I (X = H) significantly increased the GSTO1-1 inhibitory potency. We solved the cocrystal structures of new derivatives, 37 and 44, bearing an amide side chain bound to GSTO1. These new structures showed a reorientation of the Ph thiazole core of inhibitors, II and III, when compared to I (X = H). Guided by the cocrystal structure of GSTO1:III, analog IV was designed, resulting in the most potent GSTO1-1 inhibitor (IC50 = 0.22 ± 0.02 nM) known to date. We believe that our data will form the basis for future studies of developing GSTO1-1 as a new drug target for cancer therapy. The experimental process involved the reaction of 4-Phenylthiazol-2-amine(cas: 2010-06-2).Computed Properties of 2010-06-2

The Article related to phenylthiazolylacrylamide preparation anticancer glutathione transferase inhibitor, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Computed Properties of 2010-06-2

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

On June 5, 2019, Zarnegar, Zohre; Shokrani, Zahra; Safari, Javad published an article.HPLC of Formula: 2010-06-2 The title of the article was Asparagine functionalized Al2O3 nanoparticle as a superior heterogeneous organocatalyst in the synthesis of 2-aminothiazoles. And the article contained the following:

Asparagine functionalized aluminum oxide nanoparticles (Asp-Al2O3) have been prepared by a two-step procedure involving the grafting of Al2O3 with 3-chloropropyltrimethoxysilane (CPTMS) and subsequent organofunctionalization using asparagine amino acid. It is shown that Asp-Al2O3 exhibits as an active nanocatalyst for the preparation of 2-aminothiazoles is achieved by one-pot reaction of methylcarbonyls, thiourea and iodine. The structure of Asp-Al2O3 was characterized by fourier transform IR radiation (FT-TR), thermal gravimetric anal. (TGA), X-ray diffraction (XRD), scanning electron microscopic (SEM), and energy-dispersive anal. of X-ray (EDAX) analyses. Advantages of this modified methodol. include higher purity and excellent yield of products, greener and cleaner conditions, easy isolation of products and convenient manipulation. Moreover, immobilization of organocatalysts on the Al2O3 surface are stable under the catalytic reaction conditions resulting their efficient reuse. The experimental process involved the reaction of 4-Phenylthiazol-2-amine(cas: 2010-06-2).HPLC of Formula: 2010-06-2

The Article related to asparagine aluminum oxide nanoparticle preparation, aminothiazole preparation green chem, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.HPLC of Formula: 2010-06-2

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

On January 31, 2021, Zhang, Qian; Wu, Jiefei; Pan, Zexi; Zhang, Wen; Zhou, Wei published an article.Quality Control of 4-Phenylthiazol-2-amine The title of the article was A one-pot synthesis of 2-aminothiazoles via the coupling of ketones and thiourea using I2/dimethyl sulfoxide as a catalytic oxidative system. And the article contained the following:

A series of 2-aminothiazoles was prepared in moderate-to-good yields by the direct coupling of ketones and thiourea using I2/dimethyl sulfoxide as a catalytic oxidative system. This method avoids the preparation of lachrymatory and toxic α-haloketones and the use of an acid-binding agent, thus provided a more convenient approach to 2-aminothiazoles compared to the Hantzsch reaction. The experimental process involved the reaction of 4-Phenylthiazol-2-amine(cas: 2010-06-2).Quality Control of 4-Phenylthiazol-2-amine

The Article related to ketone thiourea iodine catalyst dimethyl sulfoxide oxidative coupling, aminothiazole preparation, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Quality Control of 4-Phenylthiazol-2-amine

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

On May 31, 2020, Hussein, Essam M.; Al-Rooqi, Munirah M.; Elkhawaga, Amal A.; Ahmed, Saleh A. published an article.Reference of 4-Phenylthiazol-2-amine The title of the article was Tailoring of novel biologically active molecules based on N4-substituted sulfonamides bearing thiazole moiety exhibiting unique multi-addressable biological potentials. And the article contained the following:

In the present study, a new series of 2-(4-substituted-thiazol-2-ylamino)acetamides and N-(4-substituted-thiazol-2-yl)acetamides incorporating sulfonamide moieties I (R = H, 4-bromophenyl, pyren-1-yl, etc.; R1 = CH2C(O), C(O)CH2; X = CH2, O) was designed, synthesized, well-characterized and successfully evaluated for their antimicrobial activity against multidrug resistant strains and screened for cytotoxic activity against normal lung fibroblast (WI-38), human lung carcinoma (A549), and human breast carcinoma (MDA-MB-231) cell lines. Fluorescence-activated cell sorting (FACS) anal. and mol. modeling study were performed to identify the mode of action of the novel synthesized compounds and their binding interactions with the active sites of dihydrofolate reductase enzyme (DHFR). The experimental process involved the reaction of 4-Phenylthiazol-2-amine(cas: 2010-06-2).Reference of 4-Phenylthiazol-2-amine

The Article related to acetamide aminothiazolyl sulfonyl preparation docking antibacterial antifungal antitumor activity, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Reference of 4-Phenylthiazol-2-amine

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica