Category: 202932-04-5

In an article, published in an article, once mentioned the application of 202932-04-5, Name is 5-Methyl-2-thiazolemethanol,molecular formula is C5H7NOS, is a conventional compound. this article was the specific content is as follows.Product Details of 202932-04-5

We have previously identified the 7,8,9,10-tetrahydro-7,10-ethano-1,2,4- triazolo[3,4-a]phthalazine (1) as a potent partial agonist for the 0.3 receptor subtype with 5-fold selectivity in binding affinity over alpha1. This paper describes a detailed investigation of the substituents on this core structure at both the 3- and 6-positions. Despite evaluating a wide range of groups, the maximum selectivity that could be achieved in terms of affinity for the alpha3 subtype over the alpha1 subtype was 12-fold (for 57). Although most analogues showed no selectivity in terms of efficacy, some did show partial agonism at alpha1 and antagonism at alpha3 (e.g., 25 and 75). However, two analogues tested (93 and 96), both with triazole substituents in the 6-position, showed significantly higher efficacy for the alpha3 subtype over the alpha1 subtype. This was the first indication that selectivity in efficacy in the required direction could be achieved in this series.

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Reference：
Thiazole | C3H6467NS – PubChem,
Thiazole | chemical compound | Britannica

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 202932-04-5, Name is 5-Methyl-2-thiazolemethanol, name: 5-Methyl-2-thiazolemethanol.

Compounds according to Formula (I): or a salt or prodrug thereof, have good affinity as ligands for the alpha2 and/or alpha3 subunit of the human GABA Areceptor and are useful for treatment of disorders of the central nervous system, including anxiety and convulsions.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.name: 5-Methyl-2-thiazolemethanol. In my other articles, you can also check out more blogs about 202932-04-5

Reference：
Thiazole | C3H6472NS – PubChem,
Thiazole | chemical compound | Britannica

Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 202932-04-5, C5H7NOS. A document type is Patent, introducing its new discovery., HPLC of Formula: C5H7NOS

1 -(DIHYDRONAPHTHALENYL)PYRIDONES AS MELANIN-CONCENTRATING HORMONE RECEPTOR 1 ANT­AGONISTS

Provided are 1-(dihydronaphthalenyl)pyridones which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1), pharmaceutical compositions containing them, processes for their preparation, and their use in therapy for the treatment of obesity and diabetes

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Reference：
Thiazole | C3H6469NS – PubChem,
Thiazole | chemical compound | Britannica