Category: 211940-25-9

211940-25-9, Name is 2-Ethynyl-4-methylthiazole, molecular formula is C6H5NS, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 211940-25-9, SDS of cas: 211940-25-9

A novel series of 4-thiazolylimidazoles was synthesized as transforming growth factor-beta (TGF-beta) type I receptor (also known as activin receptor-like kinase 5 or ALK5) inhibitors. These compounds were evaluated for their ALK5 inhibitory activity in an enzyme assay and their TGF-beta-induced Smad2/3 phosphorylation inhibitory activity in a cell-based assay. N-{[5-(1,3-benzothiazol-6-yl)-4-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl] methyl}butanamide 20, a potent and selective ALK5 inhibitor, exhibited good enzyme inhibitory activity (IC50 = 8.2 nM) as well as inhibitory activity against TGF-beta-induced Smad2/3 phosphorylation at a cellular level (IC50 = 32 nM).

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.SDS of cas: 211940-25-9. In my other articles, you can also check out more blogs about 211940-25-9

Reference：
Thiazole | C3H3278NS – PubChem,
Thiazole | chemical compound | Britannica

Application of 211940-25-9, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 211940-25-9, Name is 2-Ethynyl-4-methylthiazole, molecular formula is C6H5NS. In a Patent£¬once mentioned of 211940-25-9

Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 211940-25-9 is helpful to your research., Application of 211940-25-9

Reference£º
Thiazole | C3H3276NS – PubChem,
Thiazole | chemical compound | Britannica

In an article, published in an article, once mentioned the application of 211940-25-9, Name is 2-Ethynyl-4-methylthiazole,molecular formula is C6H5NS, is a conventional compound. this article was the specific content is as follows.Formula: C6H5NS

HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF PI3K-GAMMA MEDIATED DISORDERS

Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.

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Reference：
Thiazole | C3H3277NS – PubChem,
Thiazole | chemical compound | Britannica