Palladium-Catalyzed Regioselective C-H Heteroarylation of Pyridotriazoles was written by Rawat, Deepa;Semwal, Rashmi;Adimurthy, Subbarayappa. And the article was included in ChemistrySelect in 2022.Formula: C7H4FNS The following contents are mentioned in the article:
An efficient and regioselective palladium-catalyzed C-H heteroarylation of [1,2,3]triazolo[1,5-a]pyridines with benzo[b]thiophenes and benzothiazoles was described. A series of C-7 arylated [1,2,3]triazolo[1,5-a]pyridines were obtained in moderate to good yields with exclusive regioselectivity and good functional group tolerance. DBU (1,8-Diazabicyclo(5.4.0)undec-7-ene) as a base and Ag2CO3 as oxidant were the best combination for the transformation and avoided the pre-functionalized substrates. Control experiments suggested that the reaction proceeds through ionic pathway. This study involved multiple reactions and reactants, such as 7-Fluorobenzo[d]thiazole (cas: 214855-12-6Formula: C7H4FNS).
7-Fluorobenzo[d]thiazole (cas: 214855-12-6) belongs to thiazole derivatives. The thiazole ring has been identified as a central feature of numerous natural products, perhaps the most famous example of which is epothilone. Various laboratory methods exist for the organic synthesis of thiazoles. Prominent is the Hantzsch thiazole synthesis is a reaction between haloketones and thioamides.Formula: C7H4FNS
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica