Category: 2406-90-8

Synthetic Route of 2406-90-8. Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 2406-90-8, Name is 2-Chlorobenzo[d]thiazol-6-amine. In a document type is Article, introducing its new discovery.

Ultrasonics efficiently promotes the Ullmann-Goldberg condensation of 2-halogenobenzoic acids and primary aromatic amines to obtain varius N-arylanthranilic acids.

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Reference：
Thiazole | C3H3120NS – PubChem,
Thiazole | chemical compound | Britannica

In an article, published in an article, once mentioned the application of 2406-90-8, Name is 2-Chlorobenzo[d]thiazol-6-amine,molecular formula is C7H5ClN2S, is a conventional compound. this article was the specific content is as follows.SDS of cas: 2406-90-8

A compound represented by the following general formula (I) or a salt thereof: [wherein R1 and R2 represent hydrogen atom, a C1-6 alkyl group, or a group represented by the following formula (A): [wherein X1 and X2 represent hydrogen atom, or a group represented as ?N(R3)(R4) (R3 and R4 represent hydrogen atom, a C1-6 alkyl group, a C1-6 alkylcarbonyl group, or a C1-6 alkyloxycarbonyl group); and n represents an integer of 1 to 6], provided that R1 and R2 do not simultaneously represent hydrogen atom), which is a novel luciferin derivative that serves as a luciferase substrate.

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Reference：
Thiazole | C3H3138NS – PubChem,
Thiazole | chemical compound | Britannica

Electric Literature of 2406-90-8, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 2406-90-8, Name is 2-Chlorobenzo[d]thiazol-6-amine, molecular formula is C7H5ClN2S. In a Patent，once mentioned of 2406-90-8

The present invention relates to a melanin concentrating hormone antagonist compound of formula (I); wherein Ar1, L1, R1, q, X, R2, R3, R4, and R5 are as defined, or a pharmaceutically acceptable salt, solvate, or enantiomer thereof useful in the treatment, prevention or amelioration of symptoms associated with obesity and related diseases.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 2406-90-8 is helpful to your research., Electric Literature of 2406-90-8

Reference：
Thiazole | C3H3126NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 2406-90-8, Name is 2-Chlorobenzo[d]thiazol-6-amine, molecular formula is C7H5ClN2S. In a Article，once mentioned of 2406-90-8, SDS of cas: 2406-90-8

6-Nitro- and 6-amino-benzothiazoles bearing different chains in position 2 and their corresponding anthranilic acid derivatives were investigated for their in vitro antiparasitic properties against parasites of the species Leishmania infantum and Trichomonas vaginalis compared to their toxicity towards human monocytes. Biological investigations established that the antiprotozoal properties depended greatly on the chemical structure of the position 2 substitution-bearing group. Compound C1, 2-[(2-chloro-benzothiazol-6-yl) amino] benzoic acid, demonstrated an interesting antiproliferative activity towards parasites of the species T. vaginalis, while compound C11, 2-([2-[(2-hydroxyethyl) amino]-benzothiazol-6-yl] amino) benzoic acid, exhibited a promising activity against parasites of the species L. infantum in their intracellular amastigote form. Additional experiments established that compound C11, which was poorly toxic against the promastigote and the extracellular amastigote forms of the parasite, could improve host-protective mechanisms against Leishmania by preventing parasite internalization by macrophages and stimulating NO production, by means of a mechanism synergistically enhanced by the presence of gamma interferon.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.SDS of cas: 2406-90-8. In my other articles, you can also check out more blogs about 2406-90-8

Reference：
Thiazole | C3H3140NS – PubChem,
Thiazole | chemical compound | Britannica

2406-90-8, Name is 2-Chlorobenzo[d]thiazol-6-amine, molecular formula is C7H5ClN2S, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 2406-90-8, Application In Synthesis of 2-Chlorobenzo[d]thiazol-6-amine

Novel 7,8,9,10-tetrahydrothiazolo[5,4-a]acridine and 1,2,3,4-tetrahydro-12H-benzothiazolo[2,3-b]-quinazolin-12-one derivatives were synthesized in one step from the corresponding benzothiazoles. These two new tetracyclic skeletons were unambiguously characterized and are presently in pharmacological tests.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application In Synthesis of 2-Chlorobenzo[d]thiazol-6-amine. In my other articles, you can also check out more blogs about 2406-90-8

Reference：
Thiazole | C3H3131NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.2406-90-8, Name is 2-Chlorobenzo[d]thiazol-6-amine, molecular formula is C7H5ClN2S. In a Article，once mentioned of 2406-90-8, Safety of 2-Chlorobenzo[d]thiazol-6-amine

Synthesis of N-Peptide-6-Amino-d-Luciferin Conjugates with Optimized Fragment Condensation Strategy

Abstract: The synthesis of peptide-luciferin conjugates has a pivotal role in the development of bioluminescent detection systems that are based on the determination of protease enzyme activity. This work describes the optimized synthesis of an N-peptide-6-amino-d-luciferin conjugate (Fmoc-Gly-Pro-6-amino-d-luciferin) with a simple fragment condensation method in adequate yields. Fmoc-Gly-Pro-6-amino-d-luciferin was produced from a previously synthesized Fmoc-Gly-Pro-OH and also previously synthesized 6-amino-2-cyanobenzothiazole with an optimized method, to which conjugate cysteine was added in an also improved way. The resulting conjugate was successfully used in a bioluminescent system, in vitro, demonstrating the applicability of the method. Graphical Abstract: [Figure not available: see fulltext.].

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 2406-90-8 is helpful to your research., Safety of 2-Chlorobenzo[d]thiazol-6-amine

Reference：
Thiazole | C3H3137NS – PubChem,
Thiazole | chemical compound | Britannica

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.2406-90-8,2-Chlorobenzo[d]thiazol-6-amine,as a common compound, the synthetic route is as follows.

Add oxalyl chloride (10 mL, 114.6 mmol) and DMF (4 drops) to a stirring suspension of4′-fluoro-biphenyl-4-carboxylic acid (4.9 g, 22.7 mmol) in CH2Cl2 (150 mL). Stir the reaction mixture at room temperature for 3 h. Concentrate the mixture in vacuo, add n-hexane, re- concentrate, and re-dissolve in CH2Cl2. Add the resultant 4′-fluoro-biphenyl-4-carbonyl chloride solution to a mixture of 2-chloro-benzothiazol-6-ylamine (3.31 g, 17.9 mmol) and pyridine (3.0 mL) in CH2Cl2 (150 mL). Stir the reaction mixture overnight at room temperature. Dilute the reaction mixture with CH2Cl2. Wash the reaction mixture twice with LOM HCl and once with LOM NaOH. Dry the mixture over Na2SO4, concentrate in vacuo, and triturate with MeOH to yield the desired product (6.34 g, 93%). 1H NMR (400 MHz, DMSO-d6): deltaltheta.59 (s, IH), 8.69 (d, J = 1.6Hz, IH), 8.09 (d, J= 8.0Hz, 2H), 7.96 (d, J = 8.8Hz, IH), 7.87-7.79 (m, 5H), 7.38-7.31 (m, 2H)., 2406-90-8

The synthetic route of 2406-90-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; ELI LILLY AND COMPANY; WO2006/66173; (2006); A2;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica