2516-40-7, 2-Bromobenzothiazole is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
2- (3- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) phenyl) imidazo [1,2- a] pyridine 200 mg, 0.580 mmol) was added Palladium acetate (6 mg, 0.03 mmol),Triphenylphosphine (30 mg, 0.12 mmol),Sodium carbonate (124 mg, 1.16 mmol) was added, Dioxane and water in a ratio of 1: 1 in an amount of 5 mL,2-Bromobenzothiazole (124 mg, 0.580 mmol) was added,Stir at 90 ¡ã C under nitrogen gas.After the reaction is completed, the reaction mixture is cooled to room temperature. The reaction mixture is separated into water and ethyl acetate, and the extracted organic layers are combined and washed with water. After drying with magnesium sulfate, the mixture was concentrated and the concentrate was purified by silica gel column chromatography (dichloromethane: ethyl acetate, 20: 1 v / v)To obtain 2- (3- (benzothiazol-2-yl) phenyl) -8-cyanoimidazo [1,2-a] pyridine (98 mg, 59percent).
2516-40-7 2-Bromobenzothiazole 612040, athiazole compound, is more and more widely used in various.
Reference£º
Patent; Korea Research Institute of Chemical Technology; Jeon Mun-guk; Kim Gwang-rok; Huh Yun-jeong; Lee Jun-mi; (27 pag.)KR2018/101671; (2018); A;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica