Category: 29182-42-1

In an article, published in an article, once mentioned the application of 29182-42-1, Name is Ethyl 2-(benzo[d]thiazol-2-yl)acetate,molecular formula is C11H11NO2S, is a conventional compound. this article was the specific content is as follows.Quality Control of: Ethyl 2-(benzo[d]thiazol-2-yl)acetate

The invention discloses a substituted amide phenol compound and its preparation method, pharmaceutical composition and use, the compound has the following structure shown in formula I, wherein Z, L and Q are defined as in the specification and in the claims stated. The compounds of this invention and its pharmaceutical composition, can be used for preparing the prevention and/or treatment of ribonucleotide reductase related tumor. (by machine translation)

The invention discloses a substituted amide phenol compound and its preparation method, pharmaceutical composition and use, the compound has the following structure shown in formula I, wherein Z, L and Q are defined as in the specification and in the claims stated. The compounds of this invention and its pharmaceutical composition, can be used for preparing the prevention and/or treatment of ribonucleotide reductase related tumor. (by machine translation)

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Thiazole | C3H7836NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.29182-42-1, Name is Ethyl 2-(benzo[d]thiazol-2-yl)acetate, molecular formula is C11H11NO2S. In a Article£¬once mentioned of 29182-42-1, Application In Synthesis of Ethyl 2-(benzo[d]thiazol-2-yl)acetate

The adducts of Meldrum’s acid and activated methyleneazoles with 4,5-dichloro-1,2,3-dithiazolium chloride are described.Some of these adducts display an interesting equilibrium between two stereoisomers, which have either a S…O or a S…N interaction.

The adducts of Meldrum’s acid and activated methyleneazoles with 4,5-dichloro-1,2,3-dithiazolium chloride are described.Some of these adducts display an interesting equilibrium between two stereoisomers, which have either a S…O or a S…N interaction.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Application In Synthesis of Ethyl 2-(benzo[d]thiazol-2-yl)acetate, you can also check out more blogs about29182-42-1

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Thiazole | C3H7838NS – PubChem,
Thiazole | chemical compound | Britannica

29182-42-1, Name is Ethyl 2-(benzo[d]thiazol-2-yl)acetate, molecular formula is C11H11NO2S, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 29182-42-1, Quality Control of: Ethyl 2-(benzo[d]thiazol-2-yl)acetate

This invention relates to novel compounds and to pharmaceutical compositions comprising the novel compounds. More specifically, the invention relates to compounds useful as Colony Stimulating Factor 1 Receptor (cFMS) modulators (e.g. cFMS inhibitors). This invention also relates to processes for preparing the compounds, uses of the compounds in treatment and methods of treatment employing the compounds. Specifically, the invention relates to the use of the compounds for the treatment of cancer and autoimmune diseases.

This invention relates to novel compounds and to pharmaceutical compositions comprising the novel compounds. More specifically, the invention relates to compounds useful as Colony Stimulating Factor 1 Receptor (cFMS) modulators (e.g. cFMS inhibitors). This invention also relates to processes for preparing the compounds, uses of the compounds in treatment and methods of treatment employing the compounds. Specifically, the invention relates to the use of the compounds for the treatment of cancer and autoimmune diseases.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Quality Control of: Ethyl 2-(benzo[d]thiazol-2-yl)acetate. In my other articles, you can also check out more blogs about 29182-42-1

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Thiazole | C3H7824NS – PubChem,
Thiazole | chemical compound | Britannica

Related Products of 29182-42-1, An article , which mentions 29182-42-1, molecular formula is C11H11NO2S. The compound – Ethyl 2-(benzo[d]thiazol-2-yl)acetate played an important role in people’s production and life.

Polystyrene-divinylbenzene resin (PS-DVB) was functionalized with a benzothiazole group. PS-DVB with amino group was initially prepared by nitration and reduction reactions and subsequently treated with ethyl 2-benzothiazolylacetate (BA) to obtain the chelating resin with an amide linkage (BA-PS-DVB). Meanwhile, the amino-PS-DVB was diazotized and coupled with BA to obtain the chelating resin with an azo linkage (azo-BA-PS-DVB). The resins were characterized by elemental analysis and infrared spectroscopy and evaluated for their extraction of Cd(II), Cu(II) and Pb(II) ions in water before their determinations by flame atomic absorption spectrometry (FAAS). Extraction conditions were optimized for batch method such as the pH of the solution, the extraction time and the adsorption isotherm. The optimum pH for the extraction of Cd(II), Cu(II) and Pb(II) are 8.0, 7.0 and 6.0, respectively, while the equilibrium time of all ions was reached within 10-20?min. The adsorption behavior of all the metal ions followed the Langmuir adsorption isotherm. In the column method, the optimum flow rates of metal sorption onto BA-PS-DVB and azo-BA-PS-DVB columns were 2.5 and 4.0?mL min- 1. Metal ions sorbed onto columns were eluted by 0.5 to 2.0?M HNO3. The preconcentration factors of Cd(II) and Cu(II) on azo-BA-PS-DVB and Cu(II) on BA-PS-DVB were 50, 50, and 20, respectively. The present column method gave acceptable validation results: 71.2 and 74.0% recovery for Cd(II) and Cu(II) and an overall relative standard deviation (R.S.D) less than 10% (n = 15). The proposed method was applicable for determining Cu(II) in drinking water.

Polystyrene-divinylbenzene resin (PS-DVB) was functionalized with a benzothiazole group. PS-DVB with amino group was initially prepared by nitration and reduction reactions and subsequently treated with ethyl 2-benzothiazolylacetate (BA) to obtain the chelating resin with an amide linkage (BA-PS-DVB). Meanwhile, the amino-PS-DVB was diazotized and coupled with BA to obtain the chelating resin with an azo linkage (azo-BA-PS-DVB). The resins were characterized by elemental analysis and infrared spectroscopy and evaluated for their extraction of Cd(II), Cu(II) and Pb(II) ions in water before their determinations by flame atomic absorption spectrometry (FAAS). Extraction conditions were optimized for batch method such as the pH of the solution, the extraction time and the adsorption isotherm. The optimum pH for the extraction of Cd(II), Cu(II) and Pb(II) are 8.0, 7.0 and 6.0, respectively, while the equilibrium time of all ions was reached within 10-20?min. The adsorption behavior of all the metal ions followed the Langmuir adsorption isotherm. In the column method, the optimum flow rates of metal sorption onto BA-PS-DVB and azo-BA-PS-DVB columns were 2.5 and 4.0?mL min- 1. Metal ions sorbed onto columns were eluted by 0.5 to 2.0?M HNO3. The preconcentration factors of Cd(II) and Cu(II) on azo-BA-PS-DVB and Cu(II) on BA-PS-DVB were 50, 50, and 20, respectively. The present column method gave acceptable validation results: 71.2 and 74.0% recovery for Cd(II) and Cu(II) and an overall relative standard deviation (R.S.D) less than 10% (n = 15). The proposed method was applicable for determining Cu(II) in drinking water.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 29182-42-1, help many people in the next few years., Related Products of 29182-42-1

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Thiazole | C3H7848NS – PubChem,
Thiazole | chemical compound | Britannica

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.29182-42-1,Ethyl 2-(benzo[d]thiazol-2-yl)acetate,as a common compound, the synthetic route is as follows.

Step A: tert-Butyl 4-(4-formyl-3-hydroxyphenyl)piperazine-1-carboxylate (49 mg, 0.16 mmol) and ethyl 2-(benzo[d]thiazol-2-yl)acetate (35 mg, 0.16 mmol) were combined with piperidine (10 muL, 0.1 mmol) and acetic acid (6 muL, 0.1 mmol) in EtOH (1 mL). The mixture was heated at reflux for 1 h. After cooling the mixture to room temperature, a precipitate formed. The solid was collected by vacuum filtration, washed with 1:1 EtOH:H2O (1 mL) and dried under vacuum to afford tert-butyl 4-(3-(benzo[d]thiazol-2-yl)-2-oxo-2H-chromen-7-yl)piperazine-1-carboxylate.

29182-42-1, 29182-42-1 Ethyl 2-(benzo[d]thiazol-2-yl)acetate 359796, athiazole compound, is more and more widely used in various fields.

Reference£º
Patent; PTC Therapeutics, Inc.; F. Hoffmann-La Roche AG; Woll, Matthew G.; Chen, Guangming; Choi, Soongyu; Dakka, Amal; Huang, Song; Karp, Gary Mitchell; Lee, Chang-Sun; Li, Chunshi; Narasimhan, Jana; Naryshkin, Nikolai; Paushkin, Sergey; Qi, Hongyan; Turpoff, Anthony A.; Weetall, Marla L.; Welch, Ellen; Yang, Tianle; Zhang, Nanjing; Zhang, Xiaoyan; Zhao, Xin; Pinard, Emmanuel; Ratni, Hasane; (317 pag.)US9617268; (2017); B2;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica

29182-42-1, Ethyl 2-(benzo[d]thiazol-2-yl)acetate is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Tetrahydrofuran (25 mL) was added to a mixture of ethyl 2-(benzothiazol-2-yl)acetate, magnesium chloride (2.21 g, 10 mmol) and 2,6-dichloronicotinyl chloride (11 mmol). The resulting suspension was cooled in an ice bath and triethylamine (2.02 g, 20 mmol) was added dropwise at such a rate that the internal temperature did not go over 10 C. as measured with an internal thermocouple probe. Once the addition was complete, the ice bath was removed and the mixture was stirred at room temperature for 5 hours. The desired chloroester was isolated by diluting the reaction mixture with water, extraction with dichlorome thane (2×150 ml) and drying the resulting organic phase with sodium sulfate. Purification by trituration with diethyl ether yielded 2.71 g (76% based on ethyI2-(benzothiazol-2-yl)acetate) as fluffy beige crystals. IHNMR (CDC13, 400 MHz) 9.55 (IH, d, 8.4 Hz), 8.86 (IH, d, 8.4 Hz), 7.77 (IH, dd, 7.6, 1.2 Hz), 7.61 (IH, m), 7.56 (IH, d, 8.4 Hz), 7.49 (IH, m), 4.53 (2H, q, 7.2 Hz), 1.50 (3H, t, 7.2 Hz) 13CNMR (CDC13, 100 MHz) 171.1, 167.4, 163.1, 152.9, 148.4, 140.5, 137.7, 128.5, 127.8, 126.6, 123.1, 122.1, 121.7, 120.5, 106.3, 62.0, 14.7 LCMS: 359.3 (M+H)., 29182-42-1

The synthetic route of 29182-42-1 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; CYLENE PHARMACEUTICALS, INC.; WO2008/131134; (2008); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.29182-42-1,Ethyl 2-(benzo[d]thiazol-2-yl)acetate,as a common compound, the synthetic route is as follows.,29182-42-1

General procedure: To an oven-dried and argon-filled Schlenk tube was added 2-substituted benzo[d]thiazole component 1 (0.5 mmol), 2-bromoenal 2 (0.75 mmol, 1.5 equiv), triazolium salt C (0.05 mmol,10 mol%), and DIPEA (0.6 mmol, 1.2 equiv) in toluene (5 mL).The mixture was stirred at r.t. and monitored by TLC until completion of the reaction. The residue was purified by flash chromatography on silica gel [n-pentane-Et2O (10:1) or n-pentaneCH2Cl2 (1:1 to 1:2)] to afford the products 3a-k as orange oryellow solids.

The synthetic route of 29182-42-1 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Ni, Qijian; Xiong, Jiawen; Song, Xiaoxiao; Raabe, Gerhard; Enders, Dieter; Synlett; vol. 26; 11; (2015); p. 1465 – 1469;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica