Category: 3034-22-8

New learning discoveries about 3034-22-8

The synthetic route of 3034-22-8 has been constantly updated, and we look forward to future research findings.

3034-22-8, 5-Bromothiazol-2-amine is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Preparation 25; 5-Bromo-2-(2,5-dimethylpyrrol- 1 -yl)thiazoleNeutralize 2-amino-5-bromothiazole hydrobromide (2.90 g, 16.2 mmol of free amine) by treating with Na2CO3 and then add it to a mixture of hexane-2,5- dione (2.04 g, 17.8 mmol) and acetic acid (1.1 mL) in benzene. Heat the mixture EPO for 18 h in a flask equipped with a Dean-Stark trap. Filter and concentrate in vacuo to give a dark oil. Chromatograph the oil over silica eluting with 20 – 80percent EtOAc/hexanes to yield 2.95 g (71percent) of a yellow oil. MS (ES): 259 (M+l), 261 (M+H+2).

The synthetic route of 3034-22-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; ELI LILLY AND COMPANY; WO2007/2181; (2007); A2;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica