Category: 30931-67-0

Wang, Junren published the artcileEosin Y as a high-efficient photooxidase mimic for colorimetric detection of sodium azide, Category: thiazole, the publication is Analytical and Bioanalytical Chemistry (2020), 412(27), 7595-7602, database is CAplus and MEDLINE.

Abstract: The reported fluorescent dye-based artificial light-responsive oxidase mimics are suffering from their low catalytic efficiency. To overcome the limitation, we report the photooxidase-mimicking activity of Eosin Y which can catalyze the oxidation of various chromogenic substrates such as 3,3′,5,5′-tetramethylbenzydine (TMB), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS), 3,3′-diaminobenzidine (DAB), and o-phenylenediamine (OPD) by dissolved oxygen. The photooxidase-like activity of Eosin Y is highly efficient for TMB substrate, and its catalytic efficiency is higher than that of the reported fluorescein (130 fold) and 9-mesityl-10-methylacridinium ion (7.7-fold) mimetic photooxidase. Moreover, the photosensitized Eosin Y-TMB chromogenic system is utilized for colorimetric detection of highly toxic and explosive sodium azide (NaN₃) in a linear range from 5 to 500 μM with a limit of detection of 3.5 μM. The resulting colorimetric assay is selective and applied to determine NaN₃ in real lake water samples.

Analytical and Bioanalytical Chemistry published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C40H35N7O8, Category: thiazole.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica

Szponder, Tomasz published the artcileEffects of topical treatment of foot rot in sheep using ozonated olive ointment, Safety of Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), the publication is Journal of Veterinary Research (2021), 65(3), 369-374, database is CAplus and MEDLINE.

Foot rot in small ruminants is highly contagious, causes severe lameness, and impairs fertility and wool and meat production It is usually treated with parenteral antibiotics, with attendant antibiotic resistance risk, and with bactericidal footbaths, potentially harmful to humans and the environment. An alternative treatment in sheep is proposed based on repeated topical ozonated ointment application. Its effectiveness and safety were evaluated by estimation of acute-phase response, biochem. indicators of organic damage, and antioxidant/oxidant balance (AOB). The study was conducted on ten sheep with Egerton scale 2-3 lesions. Ozone application was repeated every day for seven days. Blood was drawn first (T0) after foot cleaning and before ozonation, then (T1) seven days after the first ozone application, and finally (T2) four days after the last application. High clin. effectiveness was observed, with total recovery by 28 days from the start of treatment. A significant increase in antiradical activity was noted on the basis of a 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) assay from 1.16 ± 0.04 μmolTe/mL at T0 to 1.23 ± 0.03 μmolTe/mL at T1, with a slight decrease in oxidative stress. Calculated on the basis of antiradical capacity, AOB was higher at T1 (130 ± 19%) and decreased to 110 ± 16% at T2. Calculated on the basis of reducing power, it was 169 ± 22% at T1 and 131 ± 17% at T2. These results indicated that the AOB is efficient enough to prevent oxidative organ injury and the applied doses of ozone are safe for animals.

Journal of Veterinary Research published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C6H9N3O2S, Safety of Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate).

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica

Wang, Hefei published the artcileRole of Pyrogenic Carbon in Parallel Microbial Reduction of Nitrobenzene in the Liquid and Sorbed Phases, Category: thiazole, the publication is Environmental Science & Technology (2020), 54(14), 8760-8769, database is CAplus and MEDLINE.

Surface functional groups and graphitic C comprise the electroactive components of pyrogenic C. The role of pyrogenic C with different electroactive components content in mediating electron transfer in biochem. reactions has not been systematically studied. The authors determined the pyrogenic C electron exchange capacity was 0.067-0.120 mmol e^–/g pyrogenic C with maximum elec. conductivity (EC) of 4.85 S/cm. Nitrobenzene was simultaneously reduced in liquid and sorbed phases by Shewanella oneidensis strain MR-1 in the presence of pyrogenic C. Pyrogenic C did not affect aqueous nitrobenzene reduction; reduction of sorbed nitrobenzene was much slower than that of the aqueous species. Enhancing the pyrogenic C oxygenated functional moiety content by HNO₃ oxidation elevated bio-reduction rates of aqueous and sorbed species. Anthraquinone groups were deemed the most likely oxygenated functional redox compounds based on voltammetric curve tests and spectroscopic anal. Pyrogenic C reactivity for mediating sorbed nitrobenzene reduction was pos. correlated with its EC, which was demonstrated to be related to condensed aromatic structures. This work elucidated the mechanism for pyrogenic C-mediated biotransformation of nitrobenzene and helped properly evaluate the pyrogenic C role in biogeochem. redox processes occurring in nature.

Environmental Science & Technology published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C14H21BO2, Category: thiazole.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica

Amanor-Atiemoh, Robert published the artcileEffect of simultaneous dual-frequency ultrasound aided ethanolic pretreatment on drying kinetics, bioactive compounds, antioxidant activity, and physicochemical properties of apple slices using pulsed vacuum dryer, Computed Properties of 30931-67-0, the publication is Journal of Food Process Engineering (2020), 43(11), e13535, database is CAplus.

This work aims at investigating effect of different pretreatments and varied temperature on the drying kinetics, bioactive compounds, antioxidant activity, microstructure and functional group of apple slices using pulsed vacuum dryer. Pretreated apple slices (Ethanol, US + W, and US + E) dried at varied temperature (60, 70, and 80°C) were analyzed to determine total phenolic content (TPC), total flavonoid content (TFC), 1,1-diphenyl-2-picrylhydrazyl (DPPH⁺), 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid color, microstructure and FT-IR spectroscopy. The findings revealed that US + E pretreatment significantly decreased drying time. US + E pretreatment retained TPC, TFC, DPPH⁺ and ABTS⁺ than Ethanol, US + W, and control and was further corroborated by the observed peaks as revealed by the FT-IR spectroscopy. However, drying often leads to a reduction in quality parameters as well as degradation of nutritional components of the apple. Novel pretreatment techniques like ultrasonic aided ethanolic pretreatment preceding to apple drying provides an added advantage over conventional drying methods in that it reduces dehydration time as a result of faster moisture removal, lowers energy consumption, improves process efficiency leading to industrial competiveness and it also preserves the nutritional and sensorial parameters of dried apple slices.

Journal of Food Process Engineering published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C18H24N6O6S4, Computed Properties of 30931-67-0.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica

Yin, Qiang published the artcileThe first fungal laccase with an alkaline pH optimum obtained by directed evolution and its application in indigo dye decolorization, Recommanded Product: Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), the publication is AMB Express (2019), 9(1), 1-13, database is CAplus and MEDLINE.

Engineering of fungal laccases with optimum catalytic activity at alk. pH has been a long-lasting challenge. In this study, a mutant library containing 3000 clones was obtained by error-prone PCR to adapt the optimum pH of a fungal laccase Lcc9 from the basidiomycete Coprinopsis cinerea. After three rounds of functional screening, a mutant with three amino acid changes (E116K, N229D, I393T) named PIE5 was selected. PIE5 showed an optimum pH of 8.5 and 8.0 against guaiacol and 2,6-DMP when expressed in Pichia pastoris, representing the first fungal laccase that possesses an optimum pH at an alk. condition. Site directed mutagenesis disclosed that N229D contributed the most to the optimum pH increment. A single N229D mutation caused an increase in optimum pH by 1.5 units. When used in indigo dye decolorization, PIE5 efficiently decolorized 87.1 ± 1.1% and 90.9 ± 0.3% indigo dye at the optimum conditions of pH 7.0-7.5 and 60°C, and with either Me 3,5-dimethoxy-4-hydroxybenzoate or 2,2′-azino-bis(3-ethylbenzothazoline-6-sulfonate) as the mediator. In comparison, the com. available fungal laccase TvLac from Trametes villosa decolorized 84.3 ± 1.8% of indigo dye under its optimum conditions (opt. pH 5.0 and 60°C). The properties of an alk.-dependent activity and the high indigo dye decolorization ability (1.3-fold better than the parental Lcc9) make the new fungal laccase PIE5 an alternative for specific industrial applications.

AMB Express published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C12H9NO, Recommanded Product: Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate).

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica

Zhou, Huaxi published the artcileRole of NOM in the Photolysis of Chlorine and the Formation of Reactive Species in the Solar/Chlorine System, COA of Formula: C18H24N6O6S4, the publication is ACS Omega (2022), 7(9), 7769-7776, database is CAplus and MEDLINE.

The solar/chlorine system has been proposed as a novel advanced oxidation process (AOP) for efficient pollutant degradation and water disinfection by producing a series of reactive species including hydroxyl radicals (HO^•), chlorine radicals (Cl^•), and so forth. In this study, the role of natural organic matter (NOM) in the photolysis of free available chlorine (FAC) and the formation of HO^• and Cl^• in the solar/chlorine system was investigated employing nitrobenzene and benzoic acid as selective chem. probes. The decay rate of FAC was significantly accelerated in the presence of NOM at pH 5.5 under simulated solar irradiation, likely due to the photoreaction between FAC and the photoexcited NOM. The decay rate of FAC increased upon increasing the electron-donating capacity of NOM, which indicated that phenolic components play a significant role in the photodegradation of FAC. This acceleration mechanism was further verified using 4-nitrophenol as a model phenolic compound NOM promoted Cl^• formation and quenched HO^• in the solar/chlorine system. The proposed reaction mechanism included the reaction of excited singlet phenolic compounds in NOM with FAC, which yielded Cl^•. This study provides a useful insight into future applications for using the solar/chlorine system as a novel AOP for wastewater treatment or disinfection.

ACS Omega published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C11H15NO2, COA of Formula: C18H24N6O6S4.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica

Lin, Derong published the artcileComparison of apple polyphenol-gelatin binary complex and apple polyphenol-gelatin-pectin ternary complex: Antioxidant and structural characterization, HPLC of Formula: 30931-67-0, the publication is LWT–Food Science and Technology (2021), 111740, database is CAplus.

Polyphenol-gelatin binary complex and polyphenol-gelatin-pectin ternary complex were synthesized. The differences in antioxidant activity between the binary complex and ternary complex were evaluated by using ABTS, DPPH, and reducing power assays. The differences in structural characterization between the binary complex and ternary complex were investigated by SEM (SEM), NMR (¹H and ¹³C NMR), and Fourier transform IR (FT-IR) spectroscopy. The reducing power assays of the ternary complex was greater than that of the binary complex. The maximum of ABTS•+ scavenging activity of the binary complex and the ternary complex was 98.1% and 99.3%, resp., and the maximum DPPH• scavenging activity was 84.7% and 87.6%, resp. The results of structural characterization showed that they were very similar in structure. Both complexes are mainly composed of hydrogen bonds and hydrophobic interactions, but the ternary complex is more tightly bound. In addition, the surface is smoother, and the gap is smaller.

LWT–Food Science and Technology published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C18H24N6O6S4, HPLC of Formula: 30931-67-0.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica

Shang, Yuhao published the artcilePolyphenol Profiles and Antioxidant Activities of Non-centrifugal Sugars Derived from Different Varieties of Membrane-Clarified Sugarcane Juice, Safety of Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), the publication is Sugar Tech (2022), 24(2), 614-625, database is CAplus.

The objectives of this research were to determine the sugar compositions, polyphenol contents and antioxidant effects of non-centrifugal sugars (NCS) of different sugarcane varieties. The polyphenols contents and compounds of nine NCSs obtained from the juices of different sugarcane varieties clarified with a 50 nm ceramic membrane (M-NCSs) were measured via ultraperformance liquid chromatog.-mass spectrometry (UPLC-MS). Their antioxidant activities were investigated via 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging, 2, 2′-azino-bis-(3-Et benzothia-zoline-6-sulfonic acid) (ABTS) assay, β-carotene-linoleate assays, and ferrous and cupric ion chelating assays. Results showed that the phenolic compound with the highest content was gallic acid, and all samples were abundant in phenolics, including flavonoids, with high antioxidative activities. The content of phenolics and flavonoids, ranged from 17.24 to 21.14 mg/mL and from 203.55 to 350.37μg/mL, resp. Among these M-NCSs, Funong 41 (G) genotype had the best DPPH free radical scavenging activity. The GUC 23-2 (A1) genotype showed the best ABTS free radical scavenging activity. β-Carotene-linoleate assays revealed that the 15-6013 (B2) genotype exhibited the best antioxidant activity. The Guitang 42 (E) genotype displayed the best ferrous ion chelating activity. The Zhongzhe 9 (F) genotype presented the best cupric ion chelating activity. In summary, sugarcane variety influenced the polyphenols contents and antioxidant effects of M-NCSs. This study lays a foundation for the further study of M-NCSs.

Sugar Tech published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C22H23ClN4, Safety of Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate).

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica

Sun, Mimi published the artcileA Bendable Biofuel Cell-Based Fully Integrated Biomedical Nanodevice for Point-of-Care Diagnosis of Scurvy, COA of Formula: C18H24N6O6S4, the publication is ACS Sensors (2021), 6(1), 275-284, database is CAplus and MEDLINE.

Fully integrated nanodevices that allow the complete functional implementation without an external accessory or equipment are deemed to be one of the most ideal and ultimate goals for modern nanodevice design and construction. In this work, we demonstrate the first example of a bendable biofuel cell (BFC)-based fully integrated biomedical nanodevice with simple, palm-sized, easy-to-carry, pump-free, cost-saving, and easy-to-use features for the point-of-care (POC) diagnosis of scurvy from a single drop of untreated human serum (down to 0.2μL) by integrating a bendable and disposable vitamin C/air microfluidic BFC (micro-BFC) (named iezCard) for self-powered vitamin C biosensing with a custom mini digital LED voltmeter (named iezBox) for signal processing and transmission, along with a ”built-in” biocomputing BUFFER gate for intelligent diagnosis. Under the simplicity- and practicability-oriented idea, a cost-effective strategy (e.g., biomass-derived hierarchical micro-mesoporous carbon aerogels, screen-printed technique, a single piece of Kimwipes paper, LED display, and universal components) was implemented for nanodevice design rather than any top-end or pricey method (e.g., photolithog./electron-beam evaporation, peristaltic pump, wireless system, and 3D printing technique), which enormously reduces the cost of feedstock down to ~USD 2.55 per integrated kit including a disposal iezCard (~USD 0.08 per test) and a reusable iezBox (~USD 2.47 for large-scale tests). These distinctive and attractive features allow such a fully integrated biomedical nanodevice to fully satisfy the basic requirements for POC diagnosis of scurvy from a single drop of raw human serum and make it particularly appropriate for resource-poor settings, where there is a lack of medical facilities, funds, and qualified personnel.

ACS Sensors published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C10H12F6N4O6PdS2, COA of Formula: C18H24N6O6S4.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica

Zou, Yuke published the artcileNIR-Responsive Polyurethane Nanocomposites Based on PDA@FA Nanoparticles with Synergistic Antibacterial Effect, Recommanded Product: Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), the publication is Macromolecular Chemistry and Physics, database is CAplus.

At present, high-performance antibacterial polymer materials have attracted widespread attention, possessing huge application prospects in the fields of medical and biol. science, and packaging. In this work, polydopamine nanoparticles (PDA NPs) with photothermal ability and active sites are designed to adsorb fusidic acid (FA) mols. with targeted antibacterial capability; then, polydopamine@fusidic acid (PDA@FA) is introduced into the polyurethane (PU) to obtain multifunctional and antibacterial PU materials (PUDA@FA). The structures and morphologies of PDA NPs and PDA@FA are successfully characterized by Fourier transform-IR spectroscopy and SEM. With the introduction of PDA@FA, the nano-sized reinforcement not only greatly improves the mech. properties (tensile strength 19.31 MPa and toughness 10.6 MJ m^-3) of PU film but also due to the photothermal effect of PDA NPs and the antibacterial of FA, the scavenging activities of DPPH and ABTS reach 70-85% and 55-70%, resp. The antibacterial rate of Staphylococcus aureus reaches more than 99.9% and presents long-term antibacterial ability. In this way, this work provides new guidance for the preparation of high-performance PU materials with both antibacterial and anti-oxidation properties, broadening the application scope of antibacterial materials.

Macromolecular Chemistry and Physics published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C10H14O2, Recommanded Product: Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate).

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica