Category: 315228-79-6

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The present invention relates to methods of treatment of certain metabolic diseases, and to novel compounds and their prodrugs, and/or pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds useful in treating such diseases. In particular, this invention relates to the use of novel compounds and compositions for treatment of cardiovascular diseases, diabetes, cancers, acidosis, and obesity through the inhibition of malonyl-CoA decarboxylase (MCD). These compounds have the formulae (I) and (II), wherein Y, C, R> R2, R6, and R7 are defined herein

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Reference：
Thiazole | C3H3559NS – PubChem,
Thiazole | chemical compound | Britannica

Reference of 315228-79-6. Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 315228-79-6, Name is 2-Mercaptobenzo[d]thiazole-6-carbonitrile. In a document type is Patent, introducing its new discovery.

Modulators of PPARgamma activity are used in methods of treating and/or preventing conditions such as osteoporosis, Alzheimer’s disease, psoriasis and acne, and cancer.

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Reference：
Thiazole | C3H3563NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.315228-79-6, Name is 2-Mercaptobenzo[d]thiazole-6-carbonitrile, molecular formula is C8H4N2S2. In a Patent，once mentioned of 315228-79-6, category: thiazole

Modulators of PPARgamma activity are provided which are useful in pharmaceutical compositions and methods for the treatment of conditions such as type II diabetes and obesity.

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Reference：
Thiazole | C3H3564NS – PubChem,
Thiazole | chemical compound | Britannica

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no abstract published

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Reference：
Thiazole | C3H3562NS – PubChem,
Thiazole | chemical compound | Britannica

Application of 315228-79-6. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 315228-79-6, Name is 2-Mercaptobenzo[d]thiazole-6-carbonitrile

Synthesis of 2-mercaptobenzothiazoles via DBU-promoted tandem reaction of o-haloanilines and carbon disulfide

An efficient strategy for the synthesis of a variety of 2-mercaptobenzothiazole derivatives has been developed. The reaction proceeded from o-haloaniline derivatives and carbon disulfide via a tandem reaction in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) to afford the corresponding 2-mercaptobenzothiazole derivatives in good to excellent yields.

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Reference：
Thiazole | C3H3567NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.315228-79-6, Name is 2-Mercaptobenzo[d]thiazole-6-carbonitrile, molecular formula is C8H4N2S2. In a Article£¬once mentioned of 315228-79-6, category: thiazole

A mild and practical method for the synthesis of 2-mercaptobenzothiazole has been developed by using iron as an efficient catalyst. The present tandem reaction process allows access to a wide range of 2-mercaptobenzothiazoles in good to excellent yields by the reaction of 2-haloaniline with potassium O-ethyl dithiocarbonate in the presence of FeF3 as a catalyst and 2,2?-bis(diphenylphosphino)-1,1?-binaphthyl as a ligand under an atmosphere of argon.

A mild and practical method for the synthesis of 2-mercaptobenzothiazole has been developed by using iron as an efficient catalyst. The present tandem reaction process allows access to a wide range of 2-mercaptobenzothiazoles in good to excellent yields by the reaction of 2-haloaniline with potassium O-ethyl dithiocarbonate in the presence of FeF3 as a catalyst and 2,2?-bis(diphenylphosphino)-1,1?-binaphthyl as a ligand under an atmosphere of argon.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.category: thiazole, you can also check out more blogs about315228-79-6

Reference£º
Thiazole | C3H3568NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.315228-79-6, Name is 2-Mercaptobenzo[d]thiazole-6-carbonitrile, molecular formula is C8H4N2S2. In a Article£¬once mentioned of 315228-79-6, category: thiazole

A mild and practical method for the synthesis of 2-mercaptobenzothiazole has been developed by using iron as an efficient catalyst. The present tandem reaction process allows access to a wide range of 2-mercaptobenzothiazoles in good to excellent yields by the reaction of 2-haloaniline with potassium O-ethyl dithiocarbonate in the presence of FeF3 as a catalyst and 2,2?-bis(diphenylphosphino)-1,1?-binaphthyl as a ligand under an atmosphere of argon.

A mild and practical method for the synthesis of 2-mercaptobenzothiazole has been developed by using iron as an efficient catalyst. The present tandem reaction process allows access to a wide range of 2-mercaptobenzothiazoles in good to excellent yields by the reaction of 2-haloaniline with potassium O-ethyl dithiocarbonate in the presence of FeF3 as a catalyst and 2,2?-bis(diphenylphosphino)-1,1?-binaphthyl as a ligand under an atmosphere of argon.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.category: thiazole, you can also check out more blogs about315228-79-6

Reference£º
Thiazole | C3H3568NS – PubChem,
Thiazole | chemical compound | Britannica

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We synthesized 7(S)-7-deoxy-7-arylthiolincomycin derivatives possessing a heterocyclic ring at the C-7 position via sulfur atom by either Mitsunobu reaction of 2,3,4-tris-O-(trimethylsiliyl)lincomycin or S N 2 reaction of 7-O-methanesulfonyl-2,3,4-tri-O-trimethylsiliyllincomycin. As a result, 7(S)-7-deoxy-7-arylthiolincomycin derivatives 16, 21 and 27 exhibited antibacterial activities against respiratory infection-related Gram-positive bacteria with erm gene, although clindamycin did not have any activities against those pathogens. Furthermore, 7(S)-configuration of lincomycin derivatives was found to be necessary for enhancing antibacterial activities from the comparison results of configurations of 16 (S-configuration) and 30 (R-configuration) at the 7-position.

We synthesized 7(S)-7-deoxy-7-arylthiolincomycin derivatives possessing a heterocyclic ring at the C-7 position via sulfur atom by either Mitsunobu reaction of 2,3,4-tris-O-(trimethylsiliyl)lincomycin or S N 2 reaction of 7-O-methanesulfonyl-2,3,4-tri-O-trimethylsiliyllincomycin. As a result, 7(S)-7-deoxy-7-arylthiolincomycin derivatives 16, 21 and 27 exhibited antibacterial activities against respiratory infection-related Gram-positive bacteria with erm gene, although clindamycin did not have any activities against those pathogens. Furthermore, 7(S)-configuration of lincomycin derivatives was found to be necessary for enhancing antibacterial activities from the comparison results of configurations of 16 (S-configuration) and 30 (R-configuration) at the 7-position.

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Reference£º
Thiazole | C3H3558NS – PubChem,
Thiazole | chemical compound | Britannica