Category: 348-40-3

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 348-40-3, Name is 6-Fluorobenzo[d]thiazol-2-amine, Formula: C7H5FN2S.

Synthesis, structural, conformational and pharmacological study of some carbamates derived from 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9alpha-ol

A series of benzimidazole and benzothiazole carbamates derived from 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9alpha-ol has been synthesized and studied by IR, Raman, 1H and 13C NMR spectroscopy. The compounds studied display in CDCl3 a preferred flattened chair-chair conformation. IR (at room and variable temperature) and 1H and 13C NMR data show the presence of an intramolecular NH···O=C hydrogen bond in the benzimidazole carbamates. Pharmacological assays on mice were performed to evaluate analgesic activity as well as drug-induced behavioral alterations.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Formula: C7H5FN2S. In my other articles, you can also check out more blogs about 348-40-3

Reference：
Thiazole | C3H10566NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.348-40-3, Name is 6-Fluorobenzo[d]thiazol-2-amine, molecular formula is C7H5FN2S. In a Patent，once mentioned of 348-40-3, Product Details of 348-40-3

HETEROCYCLIC COMPOUNDS AS CALCIUM CHANNEL BLOCKERS

Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type calcium channel activity are disclosed. Specifically, a series of heterocyclic compounds are disclosed of the general formula (1) where X1 and X2are linkers and W is an optionally substituted imidazolyl, oxazolyl, thiazolyl, benzimidazolyl, benzoxazolyl, or benzothiazolyl.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Product Details of 348-40-3, you can also check out more blogs about348-40-3

Reference：
Thiazole | C3H10464NS – PubChem,
Thiazole | chemical compound | Britannica

Reference of 348-40-3, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 348-40-3, Name is 6-Fluorobenzo[d]thiazol-2-amine, molecular formula is C7H5FN2S. In a Article，once mentioned of 348-40-3

Synthesis and bioactivities of alpha-aminophosphonate derivatives containing benzothiazole and thiourea moieties

The synthesis of a series of novel alpha-aminophosphonate derivatives containing benzothiazole and thiourea moieties from substituted 2-aminobenzothiazoles and synthetic intermediates O,O’-dialkylisothiocyanat- (phenyl)methylphosphonates under microwave irradiation has been demonstrated. Several salient features, such as good to excellent yields, shorter reaction times, milder reaction conditions, and simple purification procedures, make the present synthetic protocol highly attractive to access the title compounds. Bioassays indicated that most of the compounds possessed broad-spectrum insecticidal and antiviral activities against Tobacco Mosaic Virus (TMV) in vivo. Interestingly, in comparison with control insecticide Avermectin, two compounds displayed remarkably high in vitro insecticidal activities against Plutella xylostella. Furthermore, according to the results from preliminary bioassay, all were associated with moderate to good anti-TMV activities. [Supplemental materials are available for this article. Go to the publisher’s online edition of Phosphorus, Sulfur, and Silicon and the Related Elements for the following free supplemental resource: Tables S1-S4. Figures S1-S52.] Copyright Taylor and Francis Group, LLC.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 348-40-3 is helpful to your research., Reference of 348-40-3

Reference：
Thiazole | C3H10369NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 348-40-3, Name is 6-Fluorobenzo[d]thiazol-2-amine, molecular formula is C7H5FN2S. In a Article，once mentioned of 348-40-3, HPLC of Formula: C7H5FN2S

Synthesis of some new derivatives of 3,5-dimethyl azopyrazole as antifungal agents

Substituted 2-aminobenzothiazole 1 has been reacted with acetyl acetone and different hydrazines to give various (3,5- dimethyl-1-phenyl-1H-pyrazol-4-yl)- (substituted-benzothiazol-2-yl)-diazenes. IR, 1H NMR, mass spectral studies and elemental analysis have confirmed the structures of all these compounds. These compounds are evaluated for their antifungal activity.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.HPLC of Formula: C7H5FN2S, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 348-40-3, in my other articles.

Reference：
Thiazole | C3H10428NS – PubChem,
Thiazole | chemical compound | Britannica

Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 348-40-3, C7H5FN2S. A document type is Article, introducing its new discovery., Quality Control of: 6-Fluorobenzo[d]thiazol-2-amine

Synthesis of chalcone-amidobenzothiazole conjugates as antimitotic and apoptotic inducing agents

A series of chalcone-amidobenzothiazole conjugates (9a-k and 10a,b) have been synthesized and evaluated for their anticancer activity. All these compounds exhibited potent activity and the IC50 of two potential compounds (9a and 9f) against different cancer cell lines are in the range of 0.85-3.3 muM. Flow cytometric analysis revealed that these compounds induced cell cycle arrest at G2/M phase in A549 cell line leading to caspase-3 dependent apoptotic cell death. The tubulin polymerization assay (IC50 of 9a is 3.5 muM and 9f is 5.2 muM) and immuofluorescence analysis showed that these compounds effectively inhibit microtubule assembly at both molecular and cellular levels in A549 cells. Further, Annexin staining also suggested that these compounds induced cell death by apoptosis. Moreover, docking experiments have shown that they interact and bind efficiently with tubulin protein. Overall, the current study demonstrates that the synthesis of chalcone-amidobenzothiazole conjugates as promising anticancer agents with potent G2/M arrest and apoptotic-inducing activities via targeting tubulin.

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Reference：
Thiazole | C3H10562NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 348-40-3, Name is 6-Fluorobenzo[d]thiazol-2-amine, molecular formula is C7H5FN2S. In a Article，once mentioned of 348-40-3, name: 6-Fluorobenzo[d]thiazol-2-amine

New 7-(2-(benzo[d] thiazol-2-yl amino) ethoxy)-4-methyl-2H-chromen-2-ones with atypical antipsychotic activity

A new series of 7-(2-(benzo[d] thiazol-2-yl amino) ethoxy)-4-methyl-2W- chromen-2-one derivatives (4a-4k) were synthesized and evaluated for their D2 and 5HT2 antagonistic activity as a measure of atypical antipsychotic property. Most of these compounds showed dopamine D2 receptor antagonistic activity from moderate to high potency along with serotonin 5HT2 receptor blockage activity; a property necessary for atypical nature of antipshycotic agents. The D2 and 5-HT2 receptor blockage activity was evaluated by inhibition of apomorphine-induced climbing behavior and 5HTP induced head twitches in mice respectively.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.name: 6-Fluorobenzo[d]thiazol-2-amine. In my other articles, you can also check out more blogs about 348-40-3

Reference：
Thiazole | C3H10594NS – PubChem,
Thiazole | chemical compound | Britannica

In an article, published in an article, once mentioned the application of 348-40-3, Name is 6-Fluorobenzo[d]thiazol-2-amine,molecular formula is C7H5FN2S, is a conventional compound. this article was the specific content is as follows.Computed Properties of C7H5FN2S

Anti-HIV Agents: Current status and recent trends

Human immunodeficiency virus is responsible for acquired immunodeficiency syndrome (AIDS), an infectious disease that consists a serious concern worldwide for more than three decades. By the end of 2013 UNAIDS estimated that there were 35 million (range 33.2?37.2 million) adults and children living with HIV/AIDS worldwide. Despite the introduction of highly active antiretroviral therapy (HAART), the need for new anti-HIV agents is extremely high because the existing medicines do not provide the complete curation and exhibit serious side effects, and their application leads to the appearance of resistant strains. This chapter explores the medicinal chemistry efforts that gave rise to currently launched drugs as well as investigational anti-HIV agents. Currently used and studied molecular targets of antiretrovirals and the main classes of HIV-1 inhibitors are presented. Among the future prospects, we discuss the efforts directed to overcome the latent HIV infection, utilization of natural products as potential anti-HIV agents, recent trends on development of biologics as potential anti-HIV medicines, and application of computer-aided methods in the discovery of new anti-HIV drugs.

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Reference：
Thiazole | C3H10488NS – PubChem,
Thiazole | chemical compound | Britannica

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 348-40-3, Name is 6-Fluorobenzo[d]thiazol-2-amine, Quality Control of: 6-Fluorobenzo[d]thiazol-2-amine.

Synthesis and structure of some 3,4-annelated coumarin systems

Refluxing of 4-chlorocoumarin-3-carbonitrile, heteroarylamines (3-aminopyrazole, 3-aminopyrazole-4-carbonitrile, 3-amino-1,2,4-triazole-5-thiol, 2-amino-6-fluorobenzothiazole, 2-amino-pyridin-3-ol, 1-aminoisoquinoline) and the catalytic amount of trimethylamine in acetonitrile gave the corresponding 3,4-annelated coumarins 1-6 in high yields. The spectral analysis showed that 7-amino-5-oxa-7a,8,11-triazacyclopenta[b]phenantren-6-one (1) existed as enamine, 2 as a mixture of enamine 7-amino-6-oxo-5-oxa-7a,8,11-triazacyclopenta[b]phenantren-10-carbonitrile (2a) and imine 7-imino-6-oxo-7H,8H-5-oxa-7a,8,11-triazacyclopenta[b]phenantren-10- carbonitrile (2b), whereas 10-fluoro-7-imino-7H-5-oxo-12-thia-7a,13-diazaindeno[1,2-b]phenantren-6-one (4), 11-hydroxy-7-imino-7H-7a,12-diazabenzo[a]anthracen-6-one (5) and 7-imino-7H-5-oxa-7a,14-diazadibenzo[a,h]anthracen-6-on (6) took imino forms.

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Reference：
Thiazole | C3H10440NS – PubChem,
Thiazole | chemical compound | Britannica

348-40-3, Name is 6-Fluorobenzo[d]thiazol-2-amine, molecular formula is C7H5FN2S, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 348-40-3, category: thiazole

NOVEL MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER

The present disclosure relates to benzamide compounds, prodrugs of the compounds, pharmaceutical compositions containing the compounds and/or the prodrugs and methods of using the compounds, prodrugs and pharmaceutical compositions in the treatment of diseases related to lipid metabolism including diabetes, Non-Alcholic Fatty Liver Disease (NAFLD), Non-Alcholic Steathohepatitis (NASH), diseases caused by abnormal cell proliferation including cancer, psoriasis, and infectious diseases.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.category: thiazole. In my other articles, you can also check out more blogs about 348-40-3

Reference：
Thiazole | C3H10401NS – PubChem,
Thiazole | chemical compound | Britannica

Related Products of 348-40-3. Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 348-40-3, Name is 6-Fluorobenzo[d]thiazol-2-amine. In a document type is Patent, introducing its new discovery.

PEPTIDYL HETEROCYCLES USEFUL IN THE TREATMENT OF THROMBIN RELATED DISORDERS

Compounds of the Formula I: STR1 useful in the treatment of thrombin and trypsin related disorders.

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Reference：
Thiazole | C3H10506NS – PubChem,
Thiazole | chemical compound | Britannica