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Compounds of the formula: STR1 wherein R1 is (C1 to C6) alkyl. R2 is carboxy or a protected carboxy group, R3 is amino or a protected amino group and A is hydroxyimino (C1 to C6) alkylene or (C1 to C6)-alkoxyimino (C1 to C6) alkylene, and pharmaceutically acceptable salt thereof, have been found to be active against various pathogenic microorganisms.

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Reference:
Thiazole | C3H10786NS – PubChem,
Thiazole | chemical compound | Britannica

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3-Substituted-7-substituted alkanamido-3-cephem-4-carboxylic acid compounds and pharmaceutically acceptable salts thereof which have antimicrobial activities, processes for the preparation thereof, pharmaceutical compositions comprising the same, and methods of using the same therapeutically in the treatment of infections.

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Reference:
Thiazole | C3H10841NS – PubChem,
Thiazole | chemical compound | Britannica

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53266-94-7, Name is Ethyl 2-(2-aminothiazol-4-yl)acetate, molecular formula is C7H10N2O2S, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 53266-94-7, Safety of Ethyl 2-(2-aminothiazol-4-yl)acetate

The present invention concerns compounds, some of which are novel, and their pharmaceutical applications. The compounds of the invention inhibit the enzyme lactate dehydrogenase (LDH) involved both in the metabolic process of hypoxic tumour cells, and in the process used by parasitic protozoa that cause malaria to obtain most of the energy they need.

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Reference:
Thiazole | C3H10719NS – PubChem,
Thiazole | chemical compound | Britannica

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This paper reports the synthesis of five sulfonamide derivatives, the production of broad-specificity polyclonal antibodies for immunoassay of sulfonamides, and the analysis of milk samples by developed assay. The three-step synthesis procedure reported in most of the literature was adopted and modified in this study. In the procedure, the purification of the intermediate was avoided and the time of synthesis was shortened from >20 to 6-9 h with improved yields. This method is generally applicable to the synthesis of haptens containing the common structure of sulfonamides. Three haptens were coupled to keyhole limpet hemocyanin, and polyclonal antibodies were obtained from rabbits immunized with these conjugates. Using the antibodies obtained, from one of these was developed an enzyme-linked immunosorbent assay (ELISA) based on the competition between free sulfonamides and the hapten-horseradish peroxidase (HRP) conjugates. The hapten-HRP conjugate giving the best competitive results and 11 structurally different sulfonamides showed 50% inhibition at concentrations of <100 ng mL-1. After removal of the protein with acetone, milk samples were analyzed by ELISA directly; a matrix effect could be avoided when a 1:20 dilution with phosphate-buffered saline was used, and 104-131% recoveries of spiked samples were obtained. The developed immunoassay is suitable to determine sulfisozole, sulfathiazole, sulfameter, sulfamethoxypyridazine, sulfapyridine, and sulfamethizole below the maximum residue limit in milk (100 ng mL-1 of total sulfonamides) rapidly and reliably. Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Product Details of 53266-94-7. In my other articles, you can also check out more blogs about 53266-94-7

Reference:
Thiazole | C3H10691NS – PubChem,
Thiazole | chemical compound | Britannica

Properties and Exciting Facts About Ethyl 2-(2-aminothiazol-4-yl)acetate

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Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 53266-94-7, C7H10N2O2S. A document type is Patent, introducing its new discovery., Computed Properties of C7H10N2O2S

The present invention is directed to compounds of the formula I:Wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X, n and the broken lines are as defined herein which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.

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Reference:
Thiazole | C3H10714NS – PubChem,
Thiazole | chemical compound | Britannica

Brief introduction of Ethyl 2-(2-aminothiazol-4-yl)acetate

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53266-94-7, Name is Ethyl 2-(2-aminothiazol-4-yl)acetate, molecular formula is C7H10N2O2S, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 53266-94-7, SDS of cas: 53266-94-7

The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of beta3-adrenoceptor

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Reference:
Thiazole | C3H10709NS – PubChem,
Thiazole | chemical compound | Britannica

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53266-94-7, Name is Ethyl 2-(2-aminothiazol-4-yl)acetate, molecular formula is C7H10N2O2S, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 53266-94-7, COA of Formula: C7H10N2O2S

4,5-disubstituted-thizolyl amides, derivatives of 4-hydroxy-piperidine and of 4-N-methyl piperazine, were synthesized and tested as anti-inflammatory agents. Log P values were theoretically calculated and experimentally determined. These compounds were tested for antioxidant activity, as hydroxyl radical scavengers and for their ability to interact with stable 1,1-diphenyl-2-picryl hydrazyl free radical (DPPH). The effect of the synthesized compounds on inflammation, using the carrageenin induced mice paw edema model was studied. Both anti-inflammatory and antioxidant activities depended on some structural characteristics of the synthesized compounds.

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Reference:
Thiazole | C3H10839NS – PubChem,
Thiazole | chemical compound | Britannica

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Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 53266-94-7, C7H10N2O2S. A document type is Patent, introducing its new discovery., SDS of cas: 53266-94-7

Compounds of formula I or salts thereof where for example Y is a group of the formula (i) and R 1 is a group of formula (ii) are provided along with compositions containing them and processes for their preparation. The compounds are P2-purinoreceptor 7-transmembrane G-protein coupled receptor antagonists, and are useful in the treatment of inflammatory conditions.

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Reference:
Thiazole | C3H10791NS – PubChem,
Thiazole | chemical compound | Britannica

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In this paper, we present the structure-based design, synthesis and biological activity of N-pyrazole, N?-thiazole-ureas as potent inhibitors of p38alpha mitogen-activated protein kinase (p38alpha MAPK). Guided by complex crystal structures, we employed the initially identified N-aryl, N?-thiazole urea scaffold and introduced key structural elements that allowed the formation of novel hydrogen bonding interactions within the allosteric site of p38alpha, resulting in potent type III inhibitors. [4-(3-tert-Butyl-5-{[(1,3-thiazol-2-ylamino)carbonyl]amino}-1H-pyrazol-1-yl) -phenyl]acetic acid 18c was found to be the most potent compound within this series and inhibited p38alpha activity with an IC50 of 135 ± 21 nM. Its closest analog, ethyl [4-(3-tert-butyl-5-{[(1,3-thiazol-2-ylamino) carbonyl]amino}-1H-pyrazol-1-yl)phenyl]acetate 18b, effectively inhibited p38alpha mediated phosphorylation of the mitogen activated protein kinase activated protein kinase 2 (MK2) in HeLa cells.

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Reference:
Thiazole | C3H10767NS – PubChem,
Thiazole | chemical compound | Britannica

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The present invention is directed to compounds of the formula (I), wherein R1, R2, R 3, R4, R5, R6, R7, R8, R11, R12, W, X, and n are defined herein, which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.

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Reference:
Thiazole | C3H10715NS – PubChem,
Thiazole | chemical compound | Britannica