Category: 56355-62-5

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 56355-62-5, Name is Ethyl 2-bromo-5-methylthiazole-4-carboxylate, Product Details of 56355-62-5.

We describe a medicinal chemistry approach for generating a series of 2-(1H-pyrazol-1-yl)thiazoles as EP1 receptor antagonists. To improve the physicochemical properties of compound 1, we investigated its structure-activity relationships (SAR). Optimization of this lead compound provided small compound 25 which exhibited the best EP1 receptor antagonist activity and a good SAR profile.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Product Details of 56355-62-5. In my other articles, you can also check out more blogs about 56355-62-5

Reference：
Thiazole | C3H8048NS – PubChem,
Thiazole | chemical compound | Britannica

Reference of 56355-62-5. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 56355-62-5, Name is Ethyl 2-bromo-5-methylthiazole-4-carboxylate

Convenient general procedures have been developed for preparing series of thiazole-4- and -5-carboxylates containing alkyl and halogeno substituents.While both series of esters show i.r. carbonyl doublets caused by rotational isomerism, the more intense absorptions of the 4-carboxylates are the lower wavenumber components, whereas those of the 5-carboxylates are the higher wavenumber components.In both series the stronger bands arise from the thermochemically more stable forms; identification of these forms as the carbonyl O,S-syn-s-trans rotamers is more certain with the 4-carboxylates than with the 5-carboxylates.

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Reference：
Thiazole | C3H8050NS – PubChem,
Thiazole | chemical compound | Britannica