Category: 56682-07-6

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.56682-07-6, Name is 4-Methyl-5-nitrothiazol-2-amine, molecular formula is C4H5N3O2S. In a Article，once mentioned of 56682-07-6, Quality Control of: 4-Methyl-5-nitrothiazol-2-amine

Nitazoxanide has antiparasitic and antibiotic activities including activity against Mycobacterium tuberculosis. We prepared and evaluated a set of its analogues to determine the structure-activity relationship, and identified several amide- and urea-based analogues with low micromolar activity against M. tuberculosis in vitro. Pharmacokinetics in the rat suggested a path forward to obtain bioavailable compounds. The series had a good microbiological profile with bactericidal activity in vitro against replicating and nonreplicating M. tuberculosis. Analogues had limited activity against other Gram-positive bacteria but no activity against Gram-negative bacteria. Our studies identified the key liability in this series as cytotoxicity. Future work concentrating on identifying the target(s) could assist in removing activity against eukaryotic cells.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 56682-07-6 is helpful to your research., Quality Control of: 4-Methyl-5-nitrothiazol-2-amine

Reference：
Thiazole | C3H5315NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 56682-07-6, Name is 4-Methyl-5-nitrothiazol-2-amine, molecular formula is C4H5N3O2S. In a Patent£¬once mentioned of 56682-07-6, Safety of 4-Methyl-5-nitrothiazol-2-amine

The invention relates to a process for the manufacture of 1:1 metal complexes of azines of the formula STR1 wherein R1 is a hydrogen atom, an alkyl or aryl group, R2 is an isocyclic or heterocyclic radical containing a hydroxyl or mercapto group adjacent to the azomethine group, Y is the radical of a compound which contains active methylene groups, or of an aryl or heteroaryl amine, and the ring A can contain substituents that do not confer solubility in water, which process comprises reacting a compound of the formula STR2 wherein R3 is a hydrogen atom or an alkyl radical, R4 is an alkyl, aryl or heteroaryl radical or the radical of the formula STR3 or R3 and R4, together with the nitrogen atom to which they are attached, form a 5- or 6-membered heterocyclic ring, and Y has the given meaning, with a hydrazone of the formula STR4 in the presence of a transition metal donor and in a polar organic solvent, at temperatures above 100 C. Compared with pigments obtained by the prior art methods, the pigments of this invention have greater purity and better fastness properties, especially better fastness to migration, overspraying, light, atmospheric influences and heat.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Safety of 4-Methyl-5-nitrothiazol-2-amine, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 56682-07-6, in my other articles.

Reference£º
Thiazole | C3H5314NS – PubChem,
Thiazole | chemical compound | Britannica