Category: 62266-81-3

Persistence and transformation of the herbicides [¹⁴C]fenoxaprop-ethyl and [¹⁴C]fenthiaprop-ethyl in two prairie soils under laboratory and field conditions was written by Smith, Allan E.. And the article was included in Journal of Agricultural and Food Chemistry in 1985.Application In Synthesis of 6-Chlorobenzo[d]thiazol-2(3H)-one This article mentions the following:

The exptl. herbicidal esters fenoxaprop-ethyl (I) [66441-23-4] and fenthiaprop-ethyl (II) [95617-09-7] both underwent almost complete hydrolysis within 24 h to their resp. acids in soils with moisture contents >65% of field capacity. In air-dried soils, ester hydrolysis was considerably less. The fate of the 2 ¹⁴C-labeled esters was studied in 2 soil types under laboratory and field conditions. Each herbicide gave rise to the same transformation products in the laboratory and field studies. Fenthiaprop acid  [73519-50-3] and its corresponding transformation products, i.e., a phenetole [95617-11-1], phenol [70216-88-5], and a benzthiazolone [62266-81-3], have a soil persistence of about twice that of fenoxaprop acid and corresponding transformation products. In the experiment, the researchers used many compounds, for example, 6-Chlorobenzo[d]thiazol-2(3H)-one (cas: 62266-81-3Application In Synthesis of 6-Chlorobenzo[d]thiazol-2(3H)-one).

6-Chlorobenzo[d]thiazol-2(3H)-one (cas: 62266-81-3) belongs to thiazole derivatives. Thiazoles in peptides or their ability to bind proteins, DNA and RNA has led to many synthetic studies and new applications. Thiazole is a versatile building block for the construction and lead generation of new drug discoveries. Numerous diazole-based compounds are in clinical use as anticancer, antileukemic, antiinflammatory, antiviral, antifungal, antirheumatic, immunomodulator, and antiparasitic agents.Application In Synthesis of 6-Chlorobenzo[d]thiazol-2(3H)-one

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

CuI-catalyzed one-pot synthesis of benzothiazolones from 2-iodoanilines-derived carbamates and sodium sulfide was written by Li, Jiaojiao;Zhang, Yihua;Jiang, Yongwen;Ma, Dawei. And the article was included in Tetrahedron Letters in 2012.Category: thiazole This article mentions the following:

A copper-catalyzed procedure was developed for assembling benzothiazolones from Et 2-iodophenylcarbamates and sodium sulfide. A number of functional groups, such as methoxy, acyl, amide, carboxylate, trifluoromethyl, fluoro, and chloro, were tolerated under these conditions, providing benzothiazolones in good yields. In the experiment, the researchers used many compounds, for example, 6-Chlorobenzo[d]thiazol-2(3H)-one (cas: 62266-81-3Category: thiazole).

6-Chlorobenzo[d]thiazol-2(3H)-one (cas: 62266-81-3) belongs to thiazole derivatives. Thiazoles frequently appear in peptide studies. Thiazoles can also be used as protected formyl groups, which can be released in later stages of complex natural product synthesis. There are numerous natural products that possess a thiazole ring with broad pharmacological activities. Thiamine, also known as vitamin B1, possesses a thiazole ring linked with 2-methylpyrimidine-4-amine as hydrochloride salt.Category: thiazole

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Electronic spectra of benzothiazolone and its derivatives was written by Simov, D.;Antonova, A.. And the article was included in Godishnik na Sofiiskiya Universitet Sv. Kliment Okhridski, Khimicheski Fakultet in 1976.HPLC of Formula: 62266-81-3 This article mentions the following:

UV spectra are tabulated for benzothiazolones I (R = H, 3-Me, 6-Me, 5-MeO, 6-MeO, 5-Cl, 6-Cl, 6-Br, 5-Me2NSO2, 6-Me2NSO2, 5-NO2, 6-NO2) in 20% solution in EtOH and in H2O at pH 0.5, 7 and 11.5. The peaks for I (R = H, Me) came at lower wavelengths than those for the other I. In the experiment, the researchers used many compounds, for example, 6-Chlorobenzo[d]thiazol-2(3H)-one (cas: 62266-81-3HPLC of Formula: 62266-81-3).

6-Chlorobenzo[d]thiazol-2(3H)-one (cas: 62266-81-3) belongs to thiazole derivatives. The higher aromaticity of thiazole is due to delocalization of a lone pair of sulfur electrons across the ring, which is evidenced by chemical shifts of ring hydrogen at δ 7.27 and 8.77 ppm (C2 and C4), indicating diamagnetic ring current. The nitrogen in thiazole is sp2 hybridized and the lone pair of electrons localized on the nitrogen is less reactive due to increased aromatic character and decreased basicity. It is protonated and alkylated/acylated at nitrogen forming hydrochloride and quaternary thiazolium salt.HPLC of Formula: 62266-81-3

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Indolyl and dihydroindolyl N-glycinamides as potent and in vivo active NPY5 antagonists was written by Wu, Lingyun;Lu, Kai;Packiarajan, Mathivanan;Jubian, Vrej;Chandrasena, Gamini;Wolinsky, Toni C.;Walker, Mary W.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2012.Formula: C7H4ClNOS This article mentions the following:

A novel series of indolyl and dihydroindolyl glycinamides were identified as potent NPY5 antagonists with in vivo activity from screen hit I. The dihydroindolyl glycinamide II significantly inhibits NPY5 agonist induced feeding at a dose of 0.1 mg/kg. The indolyl glycinamide III also inhibits NPY5 agonist induced feeding at a dose of 1 mg/kg. Both II and III represent potential tools for further investigation into the biol. of the NPY5 receptor. In the experiment, the researchers used many compounds, for example, 6-Chlorobenzo[d]thiazol-2(3H)-one (cas: 62266-81-3Formula: C7H4ClNOS).

6-Chlorobenzo[d]thiazol-2(3H)-one (cas: 62266-81-3) belongs to thiazole derivatives. Thiazole rings are planar and aromatic. Thiazoles are characterized by larger pi-electron delocalization than the corresponding oxazoles and have therefore greater aromaticity. Various laboratory methods exist for the organic synthesis of thiazoles. Prominent is the Hantzsch thiazole synthesis is a reaction between haloketones and thioamides.Formula: C7H4ClNOS

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Ionization constants of 5- and 6-substituted benzothiazolones was written by Antonova, A.;Simov, D.. And the article was included in Monatshefte fuer Chemie in 1976.Name: 6-Chlorobenzo[d]thiazol-2(3H)-one This article mentions the following:

The ionization constants of benzothiazolone and its 5- and 6-substituted derivatives in 20 volume% EtOH are determined spectrophotometrically. The influence of the polar effects of the substituents on the ionization of the benzothiazolone is due mainly to the induction effect, confirmed by the correlation between exptl. pKa values and the Taft σ0-constants of the substituents. In the experiment, the researchers used many compounds, for example, 6-Chlorobenzo[d]thiazol-2(3H)-one (cas: 62266-81-3Name: 6-Chlorobenzo[d]thiazol-2(3H)-one).

6-Chlorobenzo[d]thiazol-2(3H)-one (cas: 62266-81-3) belongs to thiazole derivatives. The thiazole ring has been identified as a central feature of numerous natural products, perhaps the most famous example of which is epothilone. Thiazole sulfonation occurs only under forcing conditions: the action of oleum at 250 °C for 3 hours in the presence of mercury(II) sulfate leads to 65% formation of 5-thiazole sulfonic acid.Name: 6-Chlorobenzo[d]thiazol-2(3H)-one

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica