Category: 65948-19-8

Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 65948-19-8, C13H10N2OS. A document type is Patent, introducing its new discovery., Product Details of 65948-19-8

Compounds of formula (I): STR1 in which: R 1 is aryl or aromatic heterocyclic; R 2 and R 3 are hydrogen, alkyl, alkoxy, halogen, phenyl, phenoxy, C 1 -C 6 alkylthio, phenylthio, C 1 -C 6 haloalkyl, cyano or nitro, or together are alkylene optionally containing oxygen; R 4 is hydrogen, aliphatic acyl, cycloalkylcarbonyl, cycloalkoxycarbonyl, aromatic acyl, alkoxycarbonyl or benzyloxycarbonyl; R 5 and R 6 are alkyl; and X is oxygen, sulfur or methylene, have calcium channel blocking activity and can serve for the treatment or prophylaxis of cardiovascular diseases and disorders. They may be prepared by reacting a corresponding compound where R 4 is hydrogen and the aminoethyl group is replaced by hydrogen with a compound providing the aminoethyl group and the, if required, acylating the product.

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Reference：
Thiazole | C3H7416NS – PubChem,
Thiazole | chemical compound | Britannica

Synthetic Route of 65948-19-8, An article , which mentions 65948-19-8, molecular formula is C13H10N2OS. The compound – 6-Phenoxybenzo[d]thiazol-2-amine played an important role in people’s production and life.

The direct N-monomethylation of aromatic primary amines, including arylamines, arylsulfonamides and amino-azoles, using methanol as a methylating agent has been accomplished in the presence of a [CpIrCl2]2/NaOH system. From both synthetic and environmental points of view, the reaction is highly attractive because of low catalyst loading, broad substrate scope and excellent selectivities.

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Reference：
Thiazole | C3H7410NS – PubChem,
Thiazole | chemical compound | Britannica

In an article, published in an article, once mentioned the application of 65948-19-8, Name is 6-Phenoxybenzo[d]thiazol-2-amine,molecular formula is C13H10N2OS, is a conventional compound. this article was the specific content is as follows.Application In Synthesis of 6-Phenoxybenzo[d]thiazol-2-amine

The present invention provides a phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt can selectively inhibit the protein-protein interaction between KRS and a laminin receptor (LR), thereby inhibiting migration of cancer cells. Therefore, the phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt may be usefully applied for preventing or treating the diseases associated with cancer cell metastasis

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Reference：
Thiazole | C3H7409NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 65948-19-8, Name is 6-Phenoxybenzo[d]thiazol-2-amine, molecular formula is C13H10N2OS. In a Patent£¬once mentioned of 65948-19-8, Product Details of 65948-19-8

A pharmaceutical composition comprising certain benzothiazoline alkanoic acid derivatives for the prevention and treatment of various diabetic complications, said derivatives being inhibitors of aldose reductase.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Product Details of 65948-19-8, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 65948-19-8, in my other articles.

Reference£º
Thiazole | C3H7418NS – PubChem,
Thiazole | chemical compound | Britannica

Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn¡¯t involve a screen. 65948-19-8, C13H10N2OS. A document type is Patent, introducing its new discovery., SDS of cas: 65948-19-8

Compounds of formula (I): STR1 in which: R 1 is aryl or aromatic heterocyclic; R 2 and R 3 are hydrogen, alkyl, alkoxy, halogen, phenyl, phenoxy, C 1 -C 6 alkylthio, phenylthio, C 1 -C 6 haloalkyl, cyano or nitro, or together are alkylene optionally containing oxygen; R 4 is hydrogen, aliphatic acyl, cycloalkylcarbonyl, cycloalkoxycarbonyl, aromatic acyl, alkoxycarbonyl or benzyloxycarbonyl; R 5 and R 6 are alkyl; and X is oxygen, sulfur or methylene, have calcium channel blocking activity and can serve for the treatment or prophylaxis of cardiovascular diseases and disorders. They may be prepared by reacting a corresponding compound where R 4 is hydrogen and the aminoethyl group is replaced by hydrogen with a compound providing the aminoethyl group and the, if required, acylating the product.

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Reference£º
Thiazole | C3H7416NS – PubChem,
Thiazole | chemical compound | Britannica

Related Products of 65948-19-8. Let¡¯s face it, organic chemistry can seem difficult to learn. Especially from a beginner¡¯s point of view. Like 65948-19-8, Name is 6-Phenoxybenzo[d]thiazol-2-amine. In a document type is Article, introducing its new discovery.

A new series of 7-alkoxy[1,2,4]triazolo[3,4-b]benzothiazol-3(2H)-ones were synthesized and evaluated for their anticonvulsant activities. Among these compounds, 7-propoxy[1,2,4]triazolo[3,4-b]benzothiazol-3(2H)-one (4c) and 7-butoxy[1,2,4]triazolo[3,4-b]benzothiazol-3(2H)-one (4d) showed the highest activity against maximal electroshock (MES)-induced tonic extension [effective dose (ED)50: 11.4 and 13.6 mg/kg, respectively]. It is worth mentioning that compound 4d showed especially low neurotoxicity, which led to a high protective index (PI >51). The orally anticonvulsant activity data of compound 4d further confirmed its efficacy, in an MES test, and its high safety with a PI value of 50.2. In addition, the potency of compound 4h against seizures induced by pentylenetetrazole, 3-mercaptopropionic acid, and bicuculline in the chemical-induced seizure tests suggested that compound 4d may exert its anticonvulsant activity through affecting the GABAergic system.

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Reference£º
Thiazole | C3H7420NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.65948-19-8, Name is 6-Phenoxybenzo[d]thiazol-2-amine, molecular formula is C13H10N2OS. In a Article£¬once mentioned of 65948-19-8, SDS of cas: 65948-19-8

Novel non-nucleoside tricyclic platelet ADP receptor (P2Y12) antagonists have been discovered that bind reversibly and with high affinity to the platelet receptor. Condensation of various 2-aminobenzothiazoles with chlorosulfonylacetyl chloride affords these novel tricyclic heterocycles, which are novel and unpredicted products of this reaction.

Novel non-nucleoside tricyclic platelet ADP receptor (P2Y12) antagonists have been discovered that bind reversibly and with high affinity to the platelet receptor. Condensation of various 2-aminobenzothiazoles with chlorosulfonylacetyl chloride affords these novel tricyclic heterocycles, which are novel and unpredicted products of this reaction.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.SDS of cas: 65948-19-8, you can also check out more blogs about65948-19-8

Reference£º
Thiazole | C3H7414NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.65948-19-8, Name is 6-Phenoxybenzo[d]thiazol-2-amine, molecular formula is C13H10N2OS. In a Article£¬once mentioned of 65948-19-8, Application In Synthesis of 6-Phenoxybenzo[d]thiazol-2-amine

We report the synthesis and biological activity of a low molecular weight non-peptidic mimic of the analgesic peptide omega-conotoxin GVIA. The molecular weight of this compound presents a reduction by 193 g/mol compared to a previously reported lead. This compound exhibits an EC50 of 5.8 muM and is accessible in only six synthetic steps compared to the original lead (13 steps). We also report several improvements to the original synthetic route. Crown Copyright

We report the synthesis and biological activity of a low molecular weight non-peptidic mimic of the analgesic peptide omega-conotoxin GVIA. The molecular weight of this compound presents a reduction by 193 g/mol compared to a previously reported lead. This compound exhibits an EC50 of 5.8 muM and is accessible in only six synthetic steps compared to the original lead (13 steps). We also report several improvements to the original synthetic route. Crown Copyright

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 65948-19-8 is helpful to your research., Application In Synthesis of 6-Phenoxybenzo[d]thiazol-2-amine

Reference£º
Thiazole | C3H7406NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.65948-19-8, Name is 6-Phenoxybenzo[d]thiazol-2-amine, molecular formula is C13H10N2OS. In a Article£¬once mentioned of 65948-19-8, Quality Control of: 6-Phenoxybenzo[d]thiazol-2-amine

In order to improve the potency and duration of biological actions of diltiazem, a number of 1,5-benzothiazepine derivatives having the substituents at the 8 position were prepared and evaluated for their antihypertensive activity in spontaneously hypertensive rats. The introduction of methyl, ethyl, isopropyl, benzyl, methoxy, ethoxy, phenoxy, and methylthio groups increased the antihypertensive activity and prolonged duration of action, whereas cyclohexyl, cyclopentoxy, tolyloxy, p-methoxyphenoxy and phenylthio derivatives were less active than diltiazem. Among them, the 8-benzyl and phenoxy derivatives showed the most potent and long-lasting antihypertensive action.

In order to improve the potency and duration of biological actions of diltiazem, a number of 1,5-benzothiazepine derivatives having the substituents at the 8 position were prepared and evaluated for their antihypertensive activity in spontaneously hypertensive rats. The introduction of methyl, ethyl, isopropyl, benzyl, methoxy, ethoxy, phenoxy, and methylthio groups increased the antihypertensive activity and prolonged duration of action, whereas cyclohexyl, cyclopentoxy, tolyloxy, p-methoxyphenoxy and phenylthio derivatives were less active than diltiazem. Among them, the 8-benzyl and phenoxy derivatives showed the most potent and long-lasting antihypertensive action.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 65948-19-8 is helpful to your research., Quality Control of: 6-Phenoxybenzo[d]thiazol-2-amine

Reference£º
Thiazole | C3H7415NS – PubChem,
Thiazole | chemical compound | Britannica