9/22/21 News Top Picks: new discover of Methyl 2-amino-1,3-benzothiazole-6-carboxylate

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In an article, published in an article, once mentioned the application of 66947-92-0, Name is Methyl 2-amino-1,3-benzothiazole-6-carboxylate,molecular formula is C9H8N2O2S, is a conventional compound. this article was the specific content is as follows.Formula: C9H8N2O2S

A series of benzofused heterocycles was examined to replace the metabolically unstable benzyl alcohol P2/P2′ groups of DMP 323 (1). Extremely potent inhibitors of HIV protease (Ki < 0.01 nM) and excellent antiviral activity (IC90 = 8 nM) were found. An X-ray crystal structure of benzimidazolone 5a bound to HIV protease showed H-bonds to Asp30 and a bridging water molecule to Gly48. Do you like my blog? If you like, you can also browse other articles about this kind. Formula: C9H8N2O2S. Thanks for taking the time to read the blog about 66947-92-0

Reference:
Thiazole | C3H8398NS – PubChem,
Thiazole | chemical compound | Britannica

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Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Quality Control of: Methyl 2-amino-1,3-benzothiazole-6-carboxylate, you can also check out more blogs about66947-92-0

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.66947-92-0, Name is Methyl 2-amino-1,3-benzothiazole-6-carboxylate, molecular formula is C9H8N2O2S. In a Patent,once mentioned of 66947-92-0, Quality Control of: Methyl 2-amino-1,3-benzothiazole-6-carboxylate

The present invention relates to compounds having a structure of general formula (I), processes for their preparation, pharmaceutical compositions containing them as the active ingredient, to their use as medicaments and to their use in the manufacture of medicaments for use in the treatment of bacterial infections in humans and warm-blooded animals.

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Reference:
Thiazole | C3H8380NS – PubChem,
Thiazole | chemical compound | Britannica

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Reference of 66947-92-0, An article , which mentions 66947-92-0, molecular formula is C9H8N2O2S. The compound – Methyl 2-amino-1,3-benzothiazole-6-carboxylate played an important role in people’s production and life.

The syntheses of a series of 2-acetamido-6-alkoxycarbonylbenzthiazoles (12-17), 2-alkoxycarbonylamino-6-alkoxycarbonylbenzthiazoles (18-27), 2-alkoxycarbonylamino-6-benzoylbenzthiazoles (29,30), and 2,2′-dicarbalkoxyamino-6,6′-dibenzthiazolyl oxides, sulphides and sulphones (38-43) have been carried out as structural congeners of tioxidazole (2) and related anthelmintics (3 and 4).All the benzthiazoles have been evaluated for their anthelmintic activity against Ancylostoma ceylanicum in hamsters, Hymenolepis nana in mice and Litomosoides carinii in cotton rats.Compound 15 showes more than 85percent clearance of hookworms (A. ceylanicum) at an oral dose of 250 mg/kg, while compound 24 eliminates nearly 90percent of the microfilariae in blood and also kills 50percent of the adult filarial worms at an intraperitonial dose of 30 mg/kg * 5 from the cotton rats infected with Litomosoides carinii.

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Reference:
Thiazole | C3H8377NS – PubChem,
Thiazole | chemical compound | Britannica

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The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 66947-92-0 is helpful to your research., Electric Literature of 66947-92-0

Electric Literature of 66947-92-0, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 66947-92-0, Name is Methyl 2-amino-1,3-benzothiazole-6-carboxylate, molecular formula is C9H8N2O2S. In a Article,once mentioned of 66947-92-0

Synthesis and ability to displace [3H]diazepam binding from rat brain membranes of the 3-(alkoxycarbonyl)-4H-pyrimido[2,1-b]benzothiazol-4-ones 3a-p and related compounds 10-12 are described. It has been found that some compounds bind to the benzodiazepine receptor (BZR) with potency greater than chlordiazepoxide. From a structure-affinity point of view the substitution at 6-position of pyrimido[2,1-b]benzothiazole nucleus was found conductive to higher affinity. In vitro data (GABA ratio) lend support to the fact that the most active compounds 3j, 1 might possess agonist properties at BZR.

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Reference:
Thiazole | C3H8390NS – PubChem,
Thiazole | chemical compound | Britannica

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This invention relates to novel analogs of the DNA-alkylating agent CC-1065 and to their conjugates. Furthermore this invention concerns intermediates for the preparation of said agents and conjugates. The conjugates are designed to release their (multiple) payload after one or more activation steps and/or at a rate and time span controlled by the conjugate in order to selectively deliver and/or controllably release one or more of said DNA alkylating agents. The agents, conjugates, and intermediates can be used to treat an illness that is characterized by undesired (cell) proliferation. As an example, the agents and the conjugates of this invention may be used to treat a tumor.

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Reference:
Thiazole | C3H8376NS – PubChem,
Thiazole | chemical compound | Britannica

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The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 66947-92-0 is helpful to your research., Recommanded Product: 66947-92-0

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.66947-92-0, Name is Methyl 2-amino-1,3-benzothiazole-6-carboxylate, molecular formula is C9H8N2O2S. In a Patent£¬once mentioned of 66947-92-0, Recommanded Product: 66947-92-0

The present invention provides a phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt can selectively inhibit the protein-protein interaction between KRS and a laminin receptor (LR), thereby inhibiting migration of cancer cells. Therefore, the phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt may be usefully applied for preventing or treating the diseases associated with cancer cell metastasis

The present invention provides a phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt can selectively inhibit the protein-protein interaction between KRS and a laminin receptor (LR), thereby inhibiting migration of cancer cells. Therefore, the phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt may be usefully applied for preventing or treating the diseases associated with cancer cell metastasis

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 66947-92-0 is helpful to your research., Recommanded Product: 66947-92-0

Reference£º
Thiazole | C3H8381NS – PubChem,
Thiazole | chemical compound | Britannica

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The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 66947-92-0 is helpful to your research., name: Methyl 2-amino-1,3-benzothiazole-6-carboxylate

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.66947-92-0, Name is Methyl 2-amino-1,3-benzothiazole-6-carboxylate, molecular formula is C9H8N2O2S. In a Article£¬once mentioned of 66947-92-0, name: Methyl 2-amino-1,3-benzothiazole-6-carboxylate

A new organocatalytic strategy for the synthesis of enantioenriched aza-Baylis?Hillman type products via a frustrated vinylogous reaction is presented. This process proceeds under mild conditions with good yields, completed Z/E selectivity and excellent enantioselectivities. Moreover, easy derivatizations of the final products led to important building blocks of organic synthesis such as 1,3-aminoalcohols and Lewis base catalysts.

A new organocatalytic strategy for the synthesis of enantioenriched aza-Baylis?Hillman type products via a frustrated vinylogous reaction is presented. This process proceeds under mild conditions with good yields, completed Z/E selectivity and excellent enantioselectivities. Moreover, easy derivatizations of the final products led to important building blocks of organic synthesis such as 1,3-aminoalcohols and Lewis base catalysts.

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Reference£º
Thiazole | C3H8401NS – PubChem,
Thiazole | chemical compound | Britannica

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Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn¡¯t involve a screen. 66947-92-0, C9H8N2O2S. A document type is Patent, introducing its new discovery., SDS of cas: 66947-92-0

The invention provides compounds of formula (1 ) and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, and methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of AIk, AbI, Aurora-A, B-Raf, Bcr-Abl, BRK, BIk, Bmx, c-Kit, c-RAF, cSRC. CSK, FLTl, Fms, Fyn, JAK2, KDR, Lck, Lyn, PDGFRalpha, PDGFRbeta, PKCalpha, p38 (p38 MAP kinase, SAPK2alpha), Src, SIK, Syk, Tie2 and TrkB kinases

The invention provides compounds of formula (1 ) and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, and methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of AIk, AbI, Aurora-A, B-Raf, Bcr-Abl, BRK, BIk, Bmx, c-Kit, c-RAF, cSRC. CSK, FLTl, Fms, Fyn, JAK2, KDR, Lck, Lyn, PDGFRalpha, PDGFRbeta, PKCalpha, p38 (p38 MAP kinase, SAPK2alpha), Src, SIK, Syk, Tie2 and TrkB kinases

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Reference£º
Thiazole | C3H8386NS – PubChem,
Thiazole | chemical compound | Britannica

Properties and Exciting Facts About 66947-92-0

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Recommanded Product: Methyl 2-amino-1,3-benzothiazole-6-carboxylate. In my other articles, you can also check out more blogs about 66947-92-0

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 66947-92-0, Name is Methyl 2-amino-1,3-benzothiazole-6-carboxylate, molecular formula is C9H8N2O2S. In a Patent£¬once mentioned of 66947-92-0, Recommanded Product: Methyl 2-amino-1,3-benzothiazole-6-carboxylate

The invention provides bi(4-methyl-1,2,3-thiadiazole-5-phenurone) compounds and a preparation method and application thereof and relates to heterocyclic compounds containing 1,2,3-thiadiazole. The heterocyclic compounds have the following structural formula shown as in the specification of the invention. The invention discloses a structural general formula and a synthetic method of the compounds and application of the compounds as pesticides, bactericides, plant virus resisting agents and plant activating agents; a process for preparing the pesticides, the bactericides, the plant virus resistant agents and the plant activating agents by mixing the compounds with agriculturally-acceptable assistants or synergistic agents; and application of combination of the compounds and commercial pesticides, the bactericides, the plant virus resisting agents and the plant activating agents to controlling diseases, insect pests and virus diseases in agriculture, forestry and gardening and a preparation method.

The invention provides bi(4-methyl-1,2,3-thiadiazole-5-phenurone) compounds and a preparation method and application thereof and relates to heterocyclic compounds containing 1,2,3-thiadiazole. The heterocyclic compounds have the following structural formula shown as in the specification of the invention. The invention discloses a structural general formula and a synthetic method of the compounds and application of the compounds as pesticides, bactericides, plant virus resisting agents and plant activating agents; a process for preparing the pesticides, the bactericides, the plant virus resistant agents and the plant activating agents by mixing the compounds with agriculturally-acceptable assistants or synergistic agents; and application of combination of the compounds and commercial pesticides, the bactericides, the plant virus resisting agents and the plant activating agents to controlling diseases, insect pests and virus diseases in agriculture, forestry and gardening and a preparation method.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Recommanded Product: Methyl 2-amino-1,3-benzothiazole-6-carboxylate. In my other articles, you can also check out more blogs about 66947-92-0

Reference£º
Thiazole | C3H8387NS – PubChem,
Thiazole | chemical compound | Britannica

Properties and Exciting Facts About 66947-92-0

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In an article, published in an article, once mentioned the application of 66947-92-0, Name is Methyl 2-amino-1,3-benzothiazole-6-carboxylate,molecular formula is C9H8N2O2S, is a conventional compound. this article was the specific content is as follows.HPLC of Formula: C9H8N2O2S

The invention discloses a FXR receptor agonists. The invention belongs to the field of medical technology, in particular of formula (I) compound of formula, its pharmaceutically acceptable salt, an ester thereof or a stereoisomer thereof, R1 , R2 , R3 , M, L, L1 , W, A, B, Q, m, n as defined in the specification; the invention also relates to methods of preparing such compounds, pharmaceutical preparation and in medicaments for the treatment and/or prevention by the FXR receptor-mediated non-alcoholic fatty liver, primary biliary cirrhosis, disorders of the lipid metabolism, such as diabetic complications and malignant tumor diseases related to the application of the medicament. (by machine translation)

The invention discloses a FXR receptor agonists. The invention belongs to the field of medical technology, in particular of formula (I) compound of formula, its pharmaceutically acceptable salt, an ester thereof or a stereoisomer thereof, R1 , R2 , R3 , M, L, L1 , W, A, B, Q, m, n as defined in the specification; the invention also relates to methods of preparing such compounds, pharmaceutical preparation and in medicaments for the treatment and/or prevention by the FXR receptor-mediated non-alcoholic fatty liver, primary biliary cirrhosis, disorders of the lipid metabolism, such as diabetic complications and malignant tumor diseases related to the application of the medicament. (by machine translation)

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Reference£º
Thiazole | C3H8388NS – PubChem,
Thiazole | chemical compound | Britannica